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Publikationen

2020

Adlhoch C, Baylis S (2020): Letter to the Editor: The Emergence of Zoonotic Rat Hepatitis E Virus Infection.
Hepatology 72: 1155.
Online-Abstract

Agarwal S, Hanauer JDS, Frank AM, Riechert V, Thalheimer FB, Buchholz CJ (2020): In vivo generation of CAR T cells selectively in human CD4+ lymphocytes.
Mol Ther 28: 1783-1794.
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Aguirre Dávila L, Koch A, Lasch F (2020): Randomization versus Real-World Evidence.
N Engl J Med 383: e21.
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Alessandrini F, Musiol S, Schneider E, Blanco-Pérez F, Albrecht M (2020): Mimicking Antigen-Driven Asthma in Rodent Models-How Close Can We Get?.
Front Immunol 11: 575936.
Online-Abstract

Ali S, Kjeken R, Niederlaender C, Markey G, Saunders TS, Opsata M, Moltu K, Bremnes B, Grønevik E, Muusse M, Håkonsen GD, Skibeli V, Kalland ME, Wang I, Buajordet I, Urbaniak A, Johnston J, Rantell K, Kerwash E, Schuessler-Lenz M, Salmonson T, Bergh J, Gisselbrecht C, Tzogani K, Papadouli I, Pignatti F (2020): The European Medicines Agency Review of Kymriah (Tisagenlecleucel) for the Treatment of Acute Lymphoblastic Leukemia and Diffuse Large B-Cell Lymphoma.
Oncologist 25: e321-e327.
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Allgöwer SM, Hartmann CA, Holzhauser T (2020): The Development of Highly Specific and Sensitive Primers for the Detection of Potentially Allergenic Soybean (Glycine max) Using Loop-Mediated Isothermal Amplification Combined with Lateral Flow Dipstick (LAMP-LFD).
Foods 9: E423.
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Allgöwer SM, Hartmann CA, Lipinski C, Mahler V, Randow S, Völker E, Holzhauser T (2020): LAMP-LFD Based on Isothermal Amplification of Multicopy Gene ORF160b: Applicability for Highly Sensitive Low-Tech Screening of Allergenic Soybean (Glycine max) in Food.
Foods 9: E1741.
Online-Abstract

Amberger M, Ivics Z (2020): Latest Advances for the Sleeping Beauty Transposon System: 23 Years of Insomnia but Prettier than Ever: Refinement and Recent Innovations of the Sleeping Beauty Transposon System Enabling Novel, Nonviral Genetic Engineering Applications.
Bioessays 42: e2000136.
Online-Abstract

Ayasoufi K, Pfaller CK (2020): Seek and hide: the manipulating interplay of measles virus with the innate immune system.
Curr Opin Virol 41: 18-30.
Online-Abstract

Ayasoufi K, Pfaller CK, Evgin L, Khadka RH, Tritz ZP, Goddery EN, Fain CE, Yokanovich LT, Himes BT, Jin F, Zheng J, Schuelke MR, Hansen MJ, Tung W, Parney IF, Pease LR, Vile RG, Johnson AJ (2020): Brain cancer induces systemic immunosuppression through release of non-steroid soluble mediators.
Brain 143: 3629-3652.
Online-Abstract

Ayyappan Jaguva Vasudevan A, Balakrishnan K, Gertzen CGW, Borveto F, Zhang Z, Sangwiman A, Held U, Küstermann C, Banerjee S, Schumann GG, Häussinger D, Bravo IG, Gohlke H, Münk C (2020): Loop 1 of APOBEC3C regulates its antiviral activity against HIV-1.
J Mol Biol 432: 6200-6227.
Online-Abstract

Baylis SA, Miskey C, Blümel J, Kaiser M, Kapusinszky B, Delwart E (2020): Identification of a Novel Bovine Copiparvovirus in Pooled Fetal Bovine Serum.
Virus Genes 56: 522-526.
Online-Abstract

Behrensdorf-Nicol HA, Bonifas U, Klimek J, Hanschmann KM, Dorner BG, Hohenadl C, Töllner L, Kegel B, Krämer B (2020): Transferability study of the BINACLE (binding and cleavage) assay for in vitro determination of botulinum neurotoxin activity.
Biologicals 67: 81-87.
Online-Abstract

Bekeredjian-Ding I, van Molle W, Baay M, Neels P, PEI speakers and session chairs (2020): Human challenge trial workshop: Focus on quality requirements for challenge agents, Langen, Germany, October 22, 2019.
Biologicals 66: 53-61.
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Berg P, Heiden M, Müller S, Oberle D, Funk M, Keller-Stanislawski B (2020): SARS-CoV-2-Infektionen und Sicherheit von Blut und Blutkomponenten.
Bulletin zur Arzneimittelsicherheit 11: 17-19.
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Bittorf P, Bergmann T, Merlin S, Olgasi C, Pullig O, Sanzenbacher R, Zierau M, Walles H, Follenzi A, Braspenning J (2020): Regulatory-Compliant Validation of a Highly Sensitive qPCR for Biodistribution Assessment of Hemophilia A Patient Cells.
Mol Ther Methods Clin Dev 18: 176-188.
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Blanco-Rodriguez G, Gazi A, Monel B, Frabetti S, Scoca V, Mueller F, Schwartz O, Krijnse Locker J, Charneau P, Di Nunzio F (2020): Remodeling of the Core Leads HIV-1 Preintegration Complex Into the Nucleus of Human Lymphocytes.
J Virol 94: e00135-20.
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Blümel J, Schwantes A, Baylis SA, Stühler A (2020): Strategies toward virus and prion safe human platelet lysates.
Transfusion 60: 219-220.
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Börger V, Weiss DJ, Anderson JD, Borràs FE, Bussolati B, Carter DRF, Dominici M, Falcón-Pérez JM, Gimona M, Hill AF, Hoffman AM, de Kleijn D, Levine BL, Lim R, Lötvall J, Mitsialis A, Monguió-Tortajada M, Muraca M, Nieuwland R, Nowocin A, O'Driscoll L, Ortiz LA, Phinney DG, Reischl I, Rohde E, Sanzenbacher R, Théry C, Wei ST, Witwer KW, Lim SK, Giebel B (2020): ISEV and ISCT Statement on EVs From MSCs and Other Cells: Considerations for Potential Therapeutic Agents to Suppress COVID-19.
Cytotherapy 22: 482-485.
Online-Abstract

Bolden J, Knutsen C, Levin J, Milne C, Morris T, Mozier N, Spreitzer I, von Wintzingerode F (2020): Currently available recombinant alternatives to horseshoe crab blood lysates: Are they comparable for the detection of environmental bacterial endotoxins? A Review.
PDA J Pharm Sci Technol 74: 602-611.
Online-Abstract

Bonertz A, Mahler V, Vieths S (2020): New guidance on the regulation of allergen products: key aspects and outcomes.
Curr Opin Allergy Clin Immunol 20: 624-630.
Online-Abstract

Borst K, Flindt S, Blank P, Larsen PK, Chhatbar C, Skerra J, Spanier J, Hirche C, König M, Alanentalo T, Hafner M, Waibler Z, Pfeffer K, Sexl V, Sutter G, Müller W, Graalmann T, Kalinke U (2020): Selective reconstitution of IFN‑γ gene function in Ncr1+ NK cells is sufficient to control systemic vaccinia virus infection.
PLoS Pathog 16: e1008279.
Online-Abstract

Brown RJP, Tegtmeyer B, Sheldon J, Khera T, Anggakusuma, Todt D, Vieyres G, Weller R, Joecks S, Zhang Y, Sake S, Bankwitz D, Welsch K, Ginkel C, Engelmann M, Gerold G, Steinmann E, Yuan Q, Ott M, Vondran FWR, Krey T, Ströh LJ, Miskey C, Ivics Z, Herder V, Baumgärtner W, Lauber C, Seifert M, Tarr AW, McClure CP, Randall G, Baktash Y, Ploss A, Thi VLD, Michailidis E, Saeed M, Verhoye L, Meuleman P, Goedecke N, Wirth D, Rice CM, Pietschmann T (2020): Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice.
Sci Adv 6: eabd3233.
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Byskov K, Etscheid M, Kanse SM (2020): Cellular Effects of Factor VII Activating Protease (FSAP).
Thromb Res 188: 74-78.
Online-Abstract

Carpentier A, Sheldon J, Vondran FWR, Brown RJ, Pietschmann T (2020): Efficient Acute and Chronic Infection of Stem Cell-Derived Hepatocytes by Hepatitis C Virus.
Gut 69: 1659-1666.
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Cerezales M, Xanthopoulou K, Wille J, Krut O, Seifert H, Gallego L, Higgins PG (2020): Mobile Genetic Elements Harboring Antibiotic Resistance Determinants in Acinetobacter baumannii Isolates From Bolivia.
Front Microbiol 11: 919.
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Chan KH, Petrychenko V, Mueller C, Maracci C, Holtkamp W, Wilson DN, Fischer N, Rodnina MV (2020): Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun 11: 4106.
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Chanyalew M, Abebe M, Endale B, Girma S, Tasew G, van Zandbergen G, Ritter U, Gadisa E, Aseffa A, Laskay T (2020): Enhanced production of pro-inflammatory cytokines and chemokines in Ethiopian cutaneous leishmaniasis upon exposure to Leishmania aethiopica.
Cytokine 18: 155289.
Online-Abstract

Collignon O, Gartner C, Haidich AB, James Hemmings R, Hofner B, Pétavy F, Posch M, Rantell K, Roes K, Schiel A (2020): Current statistical considerations and regulatory perspectives on the planning of confirmatory basket, umbrella and platform trials.
Clin Pharmacol Ther 107: 1059-1067.
Online-Abstract

Corman VM, Rabenau HF, Adams O, Oberle D, Funk MB, Keller-Stanislawski B, Timm J, Drosten C, Ciesek S (2020): SARS-CoV-2 asymptomatic and symptomatic patients and risk for transfusion transmission.
Transfusion 60: 1119-1122.
Online-Abstract

Costa J, Bavaro SL, Benedé S, Diaz-Perales A, Bueno-Diaz C, Gelencser E, Klueber J, Larré C, Lozano-Ojalvo D, Lupi R, Mafra I, Mazzuchelli G, Molina E, Monaci L, Martin-Petraza L, Piras C, Rodrigues PM, Roncada P, Schrama D, Cirkovic-Velickovic T, Verhoeckx K, Villa C, Kuehn A, Hoffmann-Sommergruber K, Holzhauser T (2020): Are Physicochemical Properties Shaping the Allergenic Potency of Plant Allergens?..
Clin Rev Allergy Immunol Sep 2 [Epub ahead of print].
Online-Abstract

Craig-Mueller N, Hammad R, Elling R, Alzubi J, Timm B, Kolter J, Knelangen N, Bednarski C, Gläser B, Ammann S, Ivics Z, Fischer J, Speckmann C, Schwarz K, Lachmann N, Ehl S, Moritz T, Henneke P, Cathomen T (2020): Modeling MyD88 Deficiency In Vitro Provides New Insights in Its Function.
Front Immunol 11: 608802.
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Demminger DE, Walz L, Dietert K, Hoffmann H, Planz O, Gruber AD, von Messling V, Wolff T (2020): Adeno-associated Virus-Vectored Influenza Vaccine Elicits Neutralizing and Fcγ Receptor-Activating Antibodies.
EMBO Mol Med 12: e10938.
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Dickel H, Mahler V (2020): Leitliniengerechte Diagnostik der Kontaktallergie in der Praxis.
Hautarzt 71: 182-189.
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Duda H, Hesse J, Haschberger B, Hilger A, Keipert C (2020): The German Hemophilia Registry: Growing with Its Tasks.
J Clin Med 9: E3408.
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Duecker R, Baer PC, Buecker A, Huenecke S, Pfeffermann LM, Modlich U, Bakhtiar S, Bader P, Zielen S, Schubert R (2020): Hematopoietic Stem Cell Transplantation Restores Naïve T-Cell Populations in Atm-Deficient Mice and in Preemptively Treated Patients With Ataxia-Telangiectasia.
Front Immunol 10: 2785.
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Eichler H, Feyer AK, Weitmann K, Hoffmann W, Henseler O, Opitz A, Patek A, Hans DN, Schönborn L, Greinacher A (2020): Population-Based Analysis of the Impact of Demographics on the Current and Future Blood Supply in the Saarland.
Transfus Med Hemother Dec 23 [Epub ahead of print].
Online-Abstract

Erfurt-Berge C, Schmidt A, Angelovska I, Mahler V (2020): Beruflich erworbene MRSA-Besiedelung in der berufsdermatologischen Begutachtung (BK-Nr. 3101): Auswertung der DGUV BK-Dokumentation und Gutachtenfall mit arbeitsbedingter MRSA-getriggerter atopischer Dermatitis.
Hautarzt 71: 1-10.
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Etna MP, Giacomini E, Rizzo F, Severa M, Ricci D, Shaid S, Lambrigts D, Valentini S, Galli Stampino L, Alleri L, Gaggioli A, Von Hunolstein C, Spreitzer I, Coccia EM (2020): Optimization of the monocyte-activation-test for evaluating pyrogenicity of tick-borne encephalitis virus vaccine.
ALTEX 37: 532-544.
Online-Abstract

Farrukee R, Tai CM, Oh DY, Anderson DE, Gunalan V, Hibberd M, Lau GY, Barr IG, von Messling V, Maurer-Stroh S, Hurt AC (2020): Utilising animal models to evaluate oseltamivir efficacy against influenza A and B viruses with reduced in vitro susceptibility.
PLoS Pathog 16: e1008592.
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Ferastraoaru D, Bax HJ, Bergmann C, Capron M, Castells M, Dombrowicz D, Fiebiger E, Gould HJ, Hartmann K, Jappe U, Jordakieva G, Josephs DH, Levi-Schaffer F, Mahler V, Poli A, Rosenstreich D, Roth-Walter F, Shamji M, Steveling-Klein EH, Turner MC , Untersmayr E, Karagiannis SN, Jensen-Jarolim E (2020): AllergoOncology: ultra-low IgE, a potential novel biomarker in cancer-a Position Paper of the European Academy of Allergy and Clinical Immunology (EAACI).
Clin Transl Allergy 10: 32.
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Fiedler SA, Boller K, Junker AC, Kamp C, Hilger A, Schwarz W, Seitz R, Salge-Bartels U (2020): Evaluation of the in vitro function of platelet concentrates from pooled buffy coats or apheresis.
Transfus Med Hemother 47: 314-324.
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Finke J, Hitschler L, Boller K, Florin L, Lang T (2020): HPV caught in the tetraspanin web?.
Med Microbiol Immunol 209: 447-459.
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Frank AM, Braun AH, Scheib L, Agarwal S, Schneider IC, Fusil F, Perian S, Sahin U, Thalheimer FB, Verhoeyen E, Buchholz CJ (2020): Combining T-cell-specific activation and in vivo gene delivery through CD3-targeted lentiviral vectors.
Blood Adv 4: 5702-5715.
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Frank AM, Weidner T, Brynza J, Uckert W, Buchholz CJ, Hartmann J (2020): CD8-Specific Designed Ankyrin Repeat Proteins Improve Selective Gene Delivery Into Human and Primate T Lymphocytes.
Hum Gene Ther 31: 679-691.
Online-Abstract

Fuchs NV, Schieck M, Neuenkirch M, Tondera C, Schmitz H, Steinemann D, Göhring G, König R (2020): Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual.
Stem Cell Res 42: 101679.
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Fuchs NV, Schieck M, Neuenkirch M, Tondera C, Schmitz H, Wendeburg L, Steinemann D, Elpers C, Rutsch F, König R (2020): Generation of three induced pluripotent cell lines (iPSCs) from an Aicardi-Goutières syndrome (AGS) patient harboring a deletion in the genomic locus of the sterile alpha motif and HD domain containing protein 1 (SAMHD1).
Stem Cell Res 43: 101697.
Online-Abstract

Gao B, Zong W, Miskey C, Ullah N, Diaby M, Chen C, Wang X, Ivics Z, Song C (2020): Intruder (DD38E), a recently evolved sibling family of DD34E/Tc1 transposons in animals.
Mob DNA 11: 32.
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Godehardt AW, Fischer N, Rauch P, Gulich B, Boller K, Church GM, Tönjes RR (2020): Characterization of porcine endogenous retrovirus particles released by the CRISPR/Cas9 inactivated cell line PK15 clone 15.
Xenotransplantation 27: e12563.
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Godehardt AW, Ramm R, Gulich B, Tönjes RR, Hilfiker A (2020): Decellularized pig pulmonary heart valves-Depletion of nucleic acids measured by proviral PERV pol.
Xenotransplantation 27: e12565.
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Godehardt AW, Tönjes RR (2020): Xenotransplantation of Decellularized Pig Heart valves-Regulatory Aspects in Europe.
Xenotransplantation 27: e12609.
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Goeser F, Münch P, Lesker TR, Lutz PL, Krämer B, Kaczmarek DJ, Finnemann C, Nischalke HD, Geffers R, Parcina M, McHardy A, Strassburg C, Hoerauf A, Nattermann J, Bekeredjian-Ding I, Spengler U (2020): Neither Black Nor White: Do Altered Intestinal Microbiota Reflect Chronic Liver Disease Severity?.
Gut 70: 438-440.
Online-Abstract

Golsaz-Shirazi F, Asadi-Asadabad S, Sarvnaz H, Mehdi Amiri M, Hojjat-Farsangi M, Chudy M, Jeddi-Tehrani-M, Shokri F (2020): Immunoreactivity pattern of monoclonal antibodies against Hepatitis B vaccine with global Hepatitis B virus genotypes.
Clin Chim Acta 510: 203-210.
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Grabski E, Hildt E, Wagner R (2020): Zulassungsverfahren für Humanimpfstoffe in Deutschland und Europa und das Präqualifizierungsprogramm der WHO.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 4-15.
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Gurwith M, Condit RC, Excler JL, Robertson JS, Kim D, Fast PE, Drew S, Wood D, Klug B, Whelan M, Mallett Moore T, Khuri-Bulos N, Smith ER, Chen RT, Kochhar S, Brighton Collaboration Viral Vector Vaccines Safety Working Group V3SWG (2020): Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) standardized template for collection of key information for benefit-risk assessment of live-attenuated viral vaccines.
Vaccine 38: 7702-7707.
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Guth S, Hüser S, Roth A, Degen G, Diel P, Edlund K, Eisenbrand G, Engel KH, Epe B, Grune T, Heinz V, Henle T, Humpf HU, Jäger H, Joost HG, Kulling SE, Lampen A, Mally A, Marchan R, Marko D, Mühle E, Nitsche MA, Röhrdanz E, Stadler R, van Thriel C, Vieths S, Vogel RF, Wascher E, Watzl C, Nöthlings U, Hengstler JG (2020): Toxicity of Fluoride: Critical Evaluation of Evidence for Human Developmental Neurotoxicity in Epidemiological Studies, Animal Experiments and in Vitro Analyses.
Arch Toxicol 94: 1375-1415.
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Haberger V, Elgner F, Roos J, Bender D, Hildt E (2020): Regulation of the Transferrin Receptor Recycling in Hepatitis C Virus-Replicating Cells.
Front Cell Dev Biol 8: 44.
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Henss L, Scholz T, von Rhein C, Wieters I, Borgans F, Eberhardt FJ, Zacharowski K, Ciesek S, Rohde G, Vehreschild M, Stephan C, Wolf T, Hofmann-Winkler H, Scheiblauer H, Schnierle BS (2020): Analysis of humoral immune responses in SARS-CoV-2 infected patients.
J Infect Dis 223: 56-61.
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Henss L, Yue C, von Rhein C, Tschismarov R, Lewis-Ximenez LL, Dölle A, Baylis SA, Schnierle BS (2020): Analysis of humoral immune responses in chikungunya virus (CHIKV) infected patients and individuals vaccinated with a candidate CHIKV vaccine.
J Infect 221: 1713-1723.
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Hörner C, Schürmann C, Auste A, Ebenig A, Muraleedharan S, Dinnon KH, Scholz T, Herrmann M, Schnierle B, Baric RS, Mühlebach MD (2020): A Highly Immunogenic Measles Virus-based Th1-biased COVID-19 Vaccine.
Proc Natl Acad Sci USA 117: 32657-32666.
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Holzhauser T, Johnson P, Hindley JP, O'Connor G, Chan CH, Costa J, Fæste CK, Hirst BJ, Lambertini F, Miani M, Robert MC, Röder M, Ronsmans S, Bugyi Z, Tömösközi S, Flanagan SD (2020): Are current analytical methods suitable to verify VITAL® 2.0/3.0 Allergen Reference doses for EU Allergens in Foods?.
Food Chem Toxicol 145: 111709.
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Holzhauser T, Schuler F, Dudek S, Kaul S, Vieths S, Mahler V (2020): Rekombinante Allergene, Peptid und Virus-like Particles in der Immuntherapie von Allergien.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1412-1423.
Online-Abstract

Horton E, Uter W, Geier J, Ballmer-Weber B, Bauer A, Bircher A, Dickel H, Giménez-Arnau A, Goncalo M, John SM, Mahler V, Schuttelaar MLA, Simon D, Sanchez-Perez J, Rustemeyer T, Weisshaar E, Wilkinson SM (2020): Developing a cosmetic series: results from the ESSCA network, 2009-2018.
Contact Dermatitis 84: 82-94.
Online-Abstract

Iannuzzi F, Sirabella R, Canu N, Maier TJ, Annunziato L, Matrone C (2020): Fyn Tyrosine Kinase Elicits Amyloid Precursor Protein Tyr682 Phosphorylation in Neurons from Alzheimer's Disease Patients.
Cells 9: E1807.
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Ivics Z, Amberger M, Zahn T, Hildt E (2020): Immuntherapien zur Behandlung der chronischen Hepatitis-B-Virusinfektion - eine Übersicht unter besonderer Berücksichtigung von CAR-T-Zellen.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1357-1364.
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Ivics Z (2021): Potent CAR-T Cells Engineered With Sleeping Beauty Transposon Vectors Display a Central Memory Phenotype.
Gene Ther 28: 3-5.
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Jacob T, Vogel L, Reuter A, Wangorsch A, Kring C, Mahler V, Wöhrl BM (2020): Food Processing Does Not Abolish the Allergenicity of the Carrot Allergen Dau c 1: Influence of pH, Temperature, and the Food Matrix.
Mol Nutr Food Res 64: 2000334.
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Jafarzadeh L, Masoumi E, Alishah K, Mirzaei HR, Jamali A, Fallah-Mehrjardi K, Rostamian H, Khakpoor-Koosheh M, Meshkani R, Noorbakhsh F, Hadjati J (2020): Construction and Functional Characterization of a Fully Human Anti-mesothelin Chimeric Antigen Receptor (CAR) Expressing T Cell.
Iran J Allergy Asthma Immunol 19: 264-275.
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Jakubovski E, Pisarenko A, Fremer C, Haas M, May M, Schumacher C, Schindler C, Häckl S, Aguirre Davila L, Koch A, Brunnauer A, Cimpianu CL, Lutz B, Bindila L, Müller-Vahl K (2020): The CANNA-TICS Study Protocol: A Randomized Multi-Center Double-Blind Placebo Controlled Trial to Demonstrate the Efficacy and Safety of Nabiximols in the Treatment of Adults With Chronic Tic Disorders.
Front Psychiatry 11: 575826.
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Jamali A, Hadjati J, Madjd Z, Mirzaei HR, Thalheimer FB, Agarwal S, Bonig H, Ullrich E, Hartmann J (2020): Highly Efficient Generation of Transgenically Augmented CAR NK Cells Overexpressing CXCR4.
Front Immunol 11: 2028.
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Jensen-Jarolim E, Bachmann M, Bonini S, Jacobsen L, Jutel M, Klimek L, Mahler V, Mösges R, Moingeon P, O Hehir RE, Palomares O, Pfaar O, Renz H, Rhyner C, Roth-Walter F, Rudenko M, Savolainen J, Schmidt-Weber C, Traidl-Hoffmann C, Kündig T (2020): State-of-the-art in marketed adjuvants and formulations in Allergen Immunotherapy: a position paper of the European Academy of Allergy and Clinical Immunology (EAACI).
Allergy 75: 746-760.
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Jiang B, Hildt E (2020): Intracellular Trafficking of HBV Particles.
Cells 9: E2023.
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Jiang B, Wen X, Wu Q, Bender D, Carra G, Basic M, Kubesch A, Peiffer KH, Boller K, Hildt E (2020): The N-Terminus Makes the Difference: Impact of Genotype-Specific Disparities in the N-Terminal Part of The Hepatitis B Virus Large Surface Protein on Morphogenesis of Viral and Subviral Particles.
Cells 9: E1898.
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Juhl D, Chudy M, Görg S, Hennig H (2020): Prevalence of antibodies against Hepatitis D virus (HDV) in blood donors in Northern Germany.
Transfus Apher Sci 59: 102721.
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Kafere C, Tayou Tagny C, Tapko JB, Mbunkah HA, Samukange WT, Mutoti K, Mudyiwenyama L, Sumaila A, Reinhardt J (2020): Congress Report: Implementation of Blood and Blood Product Regulation Training Workshop, South Africa.
Africa Sanguine 22: 5-9.
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Kapsch AM, Farcet MR, Wieser A, Ahmad MQ, Miyabayashi T, Baylis SA, Blümel J, Kreil TR (2020): Antibody-enhanced hepatitis E virus nanofiltration during the manufacture of human immunoglobulin.
Transfusion 60: 2500-2507.
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Karamloo F, König R (2020): SARS-CoV-2 immunogenicity at the crossroads.
Allergy 75: 1822-1824.
Online-Abstract

Keipert C, Müller-Olling M, Gauly F, Arras-Reiter C, Hilger A (2020): Annual Bleeding Rates: Pitfalls of Clinical Trial Outcomes in Hemophilia Patients.
Clin Transl Sci 13: 1127-1136.
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Kempster SL, Almond N, Dimech W, Grangeot-Keros L, Huzly D, Icenogle J, Sittana El Mubarak H, Mulders MN, Nübling M (2020): WHO international standard for anti-rubella: learning from its application.
Lancet Infect Dis 20: E17-E19.
Online-Abstract

Kesselring L, Miskey C, Zuliani C, Querques I, Kapitonov V, Laukó A, Fehér A, Palazzo A, Diem T, Lustig J, Sebe A, Wang Y, Dinnyés A, Izsvák Z, Barabas O, Ivics Z (2020): A single amino acid switch converts the Sleeping Beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming.
Nucleic Acids Res 48: 316-331.
Online-Abstract

Khan AS, Blümel J, Deforce D, Gruber MF, Jungbäck C, Knezevic I, Mallet L, Mackay D, Matthijnssens J, O'Leary M, Theuns S, Victoria J, Neels P (2020): Report of the second international conference on next generation sequencing for adventitious virus detection in biologics for humans and animals.
Biologicals 67: 94-111.
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Kinast V, Plociennikowska A, Anggakusuma, Bracht T, Todt D, Brown RJP, Boldanova T, Zhang Y, Brueggemann Y, Friesland M, Engelmann M, Vieyres G, Broering R, Vondran FWR, Heim MH, Sitek B, Bartenschlager R, Pietschmann T, Steinmann E (2020): C19orf66 is an interferon-induced inhibitor of HCV replication that restricts formation of the viral replication organelle.
J Hepatol 73: 549-558.
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Kishta S, Tabll A, Omanovic Kolaric T, Smolic R, Smolic M (2020): Risk Factors Contributing to the Occurrence and Recurrence of Hepatocellular Carcinoma in Hepatitis C Virus Patients Treated with Direct-Acting Antivirals.
Biomedicines 8: 175.
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Klimek L, Hoffmann HJ, Kalpaklioglu AF, Demoly P, Agache L, Popov T, Muraro A, Schmid-Grendelmeier P, Bonini S, Bonertz A, Mahler V, Vieths S, Pfaar O, Zuberbier T, Jutel M, Schmidt-Weber C, Hellings P, Dreborg S, Bonini M, Brough HA, Bousquet J, Hoffmann-Sommergruber K, Palomares O, Ollert M, Shamji MH, Cardona V (2020): In-vivo Diagnostic Test Allergens in Europe: A Call to Action and Proposal for Recovery Plan - An EAACI Position Paper.
Allergy 75: 2161-2169.
Online-Abstract

Klug B, Schnierle B, Trebesch I (2020): Monoklonale Antikörper zur antiinfektiven Therapie.
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Kinast V, Leber SL, Brown RJP, Vieyres G, Behrendt P, Eßbach C, Strnad P, Vondran FWR, Cornberg M, Wex C, Pietschmann T, Haybaeck J, Todt D, Steinmann E (2019): Identification of Keratin 23 as a Hepatitis C Virus-Induced Host Factor in the Human Liver.
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Kleine-Tebbe J, Kaul S, Mösges R (2019): Allergen immunotherapy phase II trials: Challenges in dose finding.
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Kleinert RDV, Montoya-Diaz E, Khera T, Welsch K, Tegtmeyer B, Hoehl S, Ciesek S, Brown RJP (2019): Yellow Fever: Integrating Current Knowledge with Technological Innovations to Identify Strategies for Controlling a Re-Emerging Virus.
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Klueber J, Costa J, Randow S, Codreanu-Morel F, Verhoeckx K, Bindslev-Jensen C, Ollert M, Hoffmann-Sommergruber K, Morisset M, Holzhauser T, Kuehn A (2019): Homologous tropomyosins from vertebrate and invertebrate: Recombinant calibrator proteins in functional biological assays for tropomyosin allergenicity assessment of novel animal foods.
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Kohlscheen S, Schenk F, Rommel M, Cullmann K, Modlich U (2019): Endothelial protein C receptor supports hematopoietic stem cell engraftment and expansion in Mpl-deficient mice.
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Kraft M, Knop MP, Renaudin JM, Scherer Hofmeier K, Pföhler C, Biló MB, Lang R, Treudler R, Wagner N, Spindler T, Hourihane JO, Maris I, Koehli A, Bauer A, Lange L, Müller S, Papadopoulos NG, Wedi B, Moeser A, Ensina LF, Fernandez-Rivas M, Cichocka-Jarosz E, Christoff G, Garcia BE, Poziomkowska-Gesicka I, Cardona V, Mustakov TB, Rabe U, Mahler V, Grabenhenrich L, Dölle-Bierke S, Worm M, Network for Online Registration of Anaphylaxis (NORA) (2020): Secondary prevention measures in anaphylaxis patients: Data from the anaphylaxis registry.
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Kurtz A, Elsallab M, Sanzenbacher R, Abou-El-Enein M (2019): Linking Scattered Stem Cell-Based Data to Advance Therapeutic Development.
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Lehmann F, Rau J, Malcolm B, Sander M, von Heymann C, Moormann T, Geyer T, Balzer F, Wernecke KD, Kaufner L (2019): Why does a point of care guided transfusion algorithm not improve blood loss and transfusion practice in patients undergoing high-risk cardiac surgery? A prospective randomized controlled pilot study.
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López-Camacho C, Kim YC, Blight J, Lazaro Moreli M, Montoya-Diaz E, Huiskonen JT, Kümmerer BM, Reyes-Sandoval A (2019): Assessment of Immunogenicity and Neutralisation Efficacy of Viral-Vectored Vaccines Against Chikungunya Virus.
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Mahler V (2019): Testallergene: Aktueller Stand der Verfügbarkeit aus regulatorischer Sicht.
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Mahler V, Bonertz A, Ruoff C, Hartenstein D, Mentzer D, Kaul S, Vieths S (2019): What we learned from TAO - 10 years of German therapy allergen ordinance.
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Mahler V, Dickel H (2019): Wichtigste Kontaktallergene beim Handekzem.
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Mahler V: Topical Corticosteroids.
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Mahler V, Esch RE, Kleine-Tebbe J, Lavery WJ, Plunkett G, Vieths S, Bernstein DI (2019): Understanding Differences in Allergen Immunotherapy Products and Practices in North America and Europe.
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Mahler V (2019): Nachgefragt - Bei Epikutantests gibt es viele Fehlerquellen.
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Mahler V (2019): Präventionskonzepte für Nahrungsmittelallergien im Wandel.
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Mahler V, Nast A, Bauer A, Becker D, Brasch J, Breuer K, Dickel H, Drexler H, Elsner P, Geier J, John SM, Kreft B, Köllner A, Merk H, Ott H, Pleschka S, Portisch M, Spornraft-Ragaller P, Weisshaar E, Werfel T, Worm M, Schnuch A, Uter W (2019): S3-Leitlinie: Durchführung des Epikutantests mit Kontaktallergenen und Arzneimitteln - Kurzfassung Teil 2.
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Mahler V, Nast A, Bauer A, Becker D, Brasch J, Breuer K, Dickel H, Drexler H, Elsner P, Geier J, John SM, Kreft B, Köllner A, Merk H, Ott H, Pleschka S, Portisch M, Spornraft-Ragaller P, Weisshaar E, Werfel T, Worm M, Schnuch A, Uter W (2019): S3-Leitlinie: Durchführung des Epikutantests mit Kontaktallergenen und Arzneimitteln - Kurzfassung Teil 1.
J Dtsch Dermatol Ges 17: 1075-1093.
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Mahler V, Nast A, Uter W (2019): Methodenreport der S3‐Leitlinie zur "Durchführung des Epikutantests mit Kontaktallergenen und Arzneimitteln".
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Mahler V, Zielen S, Rosewich M (2019): Year-round treatment initiation for a 6-grasses pollen allergoid in specific immunotherapy of allergic rhinoconjunctivitis and asthma.
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Majer C, Schüssler JM, König R (2019): Intertwined: SAMHD1 cellular functions, restriction, and viral evasion strategies.
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Matheis W, Bekeredjian-Ding I (2019): Raman-Spektroskopie: 'Gefakte' Impfstoffe aufspüren.
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Mentzer D, Oberle D, Keller-Stanislawski B (2019): Daten zur Pharmakovigilanz von Impfstoffen aus dem Jahr 2017.
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Mühlebach MD, Cattaneo R: Development of Entry-Targeted Oncolytic Measles Viruses.
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Oberle D, Mentzer D, Rocha F, Streit R, Weisser K, Keller-Stanislawski B (2019): Komplikationen nach Schutzimpfungen bei Kindern und Erwachsenen mit Hinweis auf einen kausalen Zusammenhang.
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Osei Kuffour E, König R, Häussinger D, Schulz WA, Münk C (2019): ISG15 Deficiency Enhances HIV-1 Infection by Accumulating Misfolded p53.
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Pierce GF, Coffin D, Members of the WFH Gene Therapy Round Table Program Committee and Orgazining Committee, Lillicrap D, Ozelo M, Pasi J, Rotellini D, Marquez S, Sannié T, Srivastava A, den Berg M, Weill A, Almeida A, Baumann A, Brooker M, Durante L, Naccache M, Robinson F, Bagley L, Chapin J, Diop S, El Ekiaby M, Flume M, George L, Grehan J, Hawe M, High K, Hilger A, Jonsson B, Kim J, Kimmelman J, Kobelt G, Lee M, Lillicrap D, Linares A, Lozier J, Mahlangu J, Makris M, Marten K, Mathew P, Noone D, O'Hara J, Ozelo M, Ohmori T, Page D, Pasi J, Perry J, Pierce G, Hernandez P, Ragni M, Rakha M, Rayner B, Reiss U, Rollmann D, Rotellini D, Ruff P, Ruiz S, Marquez S, Sannié T, Sathyanarayanan R, Skinner M, Srivastava A, Tortella B, Tuddenham E, Valentino L, den Berg M, Vandendriessche T, Weill A, Yang R, Zelenkofske S (2019): The 1st WFH Gene Therapy Round Table: Understanding the landscape and challenges of gene therapy for haemophilia around the world.
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Süß H, Dölle-Bierke S, Geier J, Kreft B, Oppel E, Pföhler C, Skudlik C, Worm M, Mahler V (2019): Contact urticaria: Frequency, elicitors and cofactors in three cohorts (Information Network of Departments of Dermatology; Network of Anaphylaxis; and Department of Dermatology, University Hospital Erlangen, Germany).
Contact Dermatitis 81: 341-353.
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Tan CW, Wittwer K, Lim XF, Uehara A, Mani S, Wang LF, Anderson DE (2019): Serological evidence and experimental infection of cynomolgus macaques with pteropine orthoreovirus reveal monkeys as potential hosts for transmission to humans.
Emerg Microbes Infect 8: 787-795.
Online-Abstract

Toda M, Hellwig M, Henle T, Vieths S (2019): Influence of the Maillard Reaction on the Allergenicity of Food Proteins and the Development of Allergic Inflammation.
Curr Allergy Asthma Rep 19: 4.
Text

Toots M, Yoon JJ, Cox RM, Hart M, Sticher ZM, Makhsous N, Plesker R, Barrena AH, Reddy PG, Mitchell DG, Shean RC, Bluemling GR, Kolykhalov AA, Greninger AL, Natchus MG, Painter GR, Plemper RK (2019): Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia.
Sci Transl Med 11: eaax5866.
Online-Abstract

Trösemeier JH, Rudorf S, Loessner H, Hofner B, Reuter A, Schulenborg T, Koch I, Bekeredjian-Ding I, Lipowsky R, Kamp C (2019): Optimizing the dynamics of protein expression.
Sci Rep 9: 7511.
Text

Vermeer NS, Giezen TJ, Zastavnik S, Wolff-Holz E, Hidalgo-Simon A (2019): Identifiability of biologicals in adverse drug reaction reports received from European clinical practice.
Clin Pharmacol Ther 105: 962-969.
Online-Abstract

Volkers P, Hanschmann KM, Chambost H, Collins PW, Demiguel V, Hart DP, Hay CRM, Goudemand J, Ljung R, Palmer BP, Santagostino E, van Hardeveld EM, van den Berg M, Keller-Stanislawski B (2019): Recombinant factor VIII products and inhibitor development in previously untreated patients with severe haemophilia A: Combined analysis of three studies.
Haemophilia 25: 398-407.
Online-Abstract

Wagner R, Hildt E (2019): Zusammensetzung und Wirkmechanismen von Adjuvanzien in zugelassenen viralen Impfstoffen.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 62: 462-471.
Online-Abstract

Walter C, Ott H, Ahrens B (2019): Urtikaria - Ein Vorschlag zur Umsetzung der aktuell überarbeiteten europäischen Leitlinie in die pädiatrische Praxis.
Pädiatrische Allergologie 2019: 4-11.
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Weisser K, Göen T, Oduro JD, Wangorsch G, Hanschmann KO, Keller-Stanislawski B (2019): Aluminium toxicokinetics after intramuscular, subcutaneous, and intravenous injection of Al citrate solution in rats.
Arch Toxicol 93: 37-47.
Online-Abstract

Weisser K, Göen T, Oduro JD, Wangorsch G, Hanschmann KO, Keller-Stanislawski B (2019): Aluminium in plasma and tissues after intramuscular injection of adjuvanted human vaccines in rats.
Arch Toxicol 93: 2787-2796.
Online-Abstract

Weisser K, Keller-Stanislawski B (2019): Daten zur Aluminiumkinetik nach Verabreichung von aluminiumbasierten Adjuvanzien in Ratten.
Bulletin zur Arzneimittelsicherheit 10: 31-34.
Text

Wen X, Sun D, Guo J, Elgner F, Wang M, Hildt E, Cheng A (2019): Multifunctionality of structural proteins in the enterovirus life cycle.
Future Microbiol 14: 1147-1157.
Online-Abstract

Wenzel A, Schwedinger E, Kulezic B, Cußler K (2019): Pharmakovigilanzreport Tierimpfstoffe: Analyse der Nebenwirkungsmeldungen aus den Jahren 2016 und 2017.
DTBl 67: 1270-1276.
Volltext

Wilkinson M, Goncalo M, Aerts O, Badulici S, Bennike NH, Bruynzeel D, Dickel H, Garcia-Abujeta JL, Gimenez-Arnau AM, Hamman C, Isaksson M, Johansen JD, Mahler V, Niklasson B, Orton D, Pigatto P, Ponyai G, Rustemeyer T, Schuttelaar MLA, Spiewak R, Thyssen JP, Uter W (2019): The European baseline series and recommended additions: 2019.
Contact Dermatitis 80: 1-4.

Wolff-Holz E, Müller-Berghaus J, Weise M (2019): Biosimilars in der Onkologie (Teil 1): Dank strenger Regulierung keine zweite Wahl.
Dtsch Arztebl 116: 28-34.
Online-Abstract

Wolff-Holz E, Müller-Berghaus J, Weise M (2019): Biosimilars in der Onkologie (Teil 2): Wie man die Biosimilarität wissenschaftlich bestätigt.
Dtsch Arztebl 116: 14-19.
Online-Abstract

Wolff-Holz E, Tiitso K, Vleminckcx C, Weise M (2019): Evolution of the EU Biosimilar Framework: Past and Future.
BioDrugs 33: 621-634.
Text

Yakoub A, Schülke S (2019): A model for apoptotic-mediated adaptive immune evasion via CD80–CTLA-4 signaling.
Front Pharmacol 10: 562.
Online-Abstract

Yue C, Teitz S, Miyabashi T, Boller K, Lewis-Ximinez LL, Baylis SA, Blümel J (2019): Inactivation and Removal of Chikungunya Virus and Mayaro Virus from Plasma-derived Medicinal Products.
Viruses 11: 234.
Text

Ziegler A, Hinz T, Kalinke U (2019): RNA-Based Adjuvants: Immunoenhancing Effect on Antiviral Vaccines and Regulatory Considerations.
Crit Rev Immunol 39: 1-14.
Online-Abstract

Forschung beim Präsidenten: Molekulare Biotechnologie und Gentherapie

Agarwal S, Hanauer JDS, Frank AM, Riechert V, Thalheimer FB, Buchholz CJ (2020): In vivo generation of CAR T cells selectively in human CD4+ lymphocytes.
Mol Ther 28: 1783-1794.
Text

Agarwal S, Weidner T, Thalheimer FB, Buchholz CJ (2019): In vivo generated human CAR T cells eradicate tumor cells.
Oncoimmunology 8: e1671761.
Online-Abstract

Frank AM, Braun AH, Scheib L, Agarwal S, Schneider IC, Fusil F, Perian S, Sahin U, Thalheimer FB, Verhoeyen E, Buchholz CJ (2020): Combining T-cell-specific activation and in vivo gene delivery through CD3-targeted lentiviral vectors.
Blood Adv 4: 5702-5715.
Text

Frank AM, Weidner T, Brynza J, Uckert W, Buchholz CJ, Hartmann J (2020): CD8-Specific Designed Ankyrin Repeat Proteins Improve Selective Gene Delivery Into Human and Primate T Lymphocytes.
Hum Gene Ther 31: 679-691.
Online-Abstract

Hartmann J, Thalheimer FB, Höpfner F, Kerzel T, Khodosevich K, García-González D, Monyer H, Diester I, Büning H, Carette JE, Fries P, Buchholz CJ (2019): GluA4-Targeted AAV Vectors Deliver Genes Selectively to Interneurons while Relying on the AAV Receptor for Entry.
Mol Ther Methods Clin Dev 14: 252-260.
Text

Jafarzadeh L, Masoumi E, Alishah K, Mirzaei HR, Jamali A, Fallah-Mehrjardi K, Rostamian H, Khakpoor-Koosheh M, Meshkani R, Noorbakhsh F, Hadjati J (2020): Construction and Functional Characterization of a Fully Human Anti-mesothelin Chimeric Antigen Receptor (CAR) Expressing T Cell.
Iran J Allergy Asthma Immunol 19: 264-275.
Online-Abstract

Jamali A, Hadjati J, Madjd Z, Mirzaei HR, Thalheimer FB, Agarwal S, Bonig H, Ullrich E, Hartmann J (2020): Highly Efficient Generation of Transgenically Augmented CAR NK Cells Overexpressing CXCR4.
Front Immunol 11: 2028.
Online-Abstract

Jamali A, Kapitza L, Schaser T, Johnston ICD, Buchholz CJ, Hartmann J (2019): Highly Efficient and Selective CAR-Gene Transfer Using CD4- and CD8-Targeted Lentiviral Vectors.
Mol Ther Methods Clin Dev 13: 371-379.
Text

Michels A, Hartmann J, Buchholz CJ (2020): Chimäre Antigenrezeptoren (CARs) in der Onkologie: eine Übersicht zu klinischer Anwendung und neuen Entwicklungen.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1331-1340.
Online-Abstract

Patasic L, Seifried J, Bezler V, Kaljanac M, Schneider IC, Schmitz H, Tondera C, Hartmann J, Hombach A, Buchholz CJ, Abken H, König R, Cichutek K (2020): Designed Ankyrin Repeat Protein (DARPin) to target chimeric antigen receptor (CAR)-redirected T cells towards CD4 + T cells to reduce the latent HIV + cell reservoir.
Med Microbiol Immunol 209: 681-691.
Online-Abstract

Reul J, Frisch J, Engeland CE, Thalheimer FB, Hartmann J, Ungerechts G, Buchholz CJ (2019): Tumor-Specific Delivery of Immune Checkpoint Inhibitors by Engineered AAV Vectors.
Front Oncol 9: 52.
Text

Forschung beim Vizepräsidenten: Molekulare Allergologie

Alessandrini F, Musiol S, Schneider E, Blanco-Pérez F, Albrecht M (2020): Mimicking Antigen-Driven Asthma in Rodent Models-How Close Can We Get?.
Front Immunol 11: 575936.
Online-Abstract

Blanco-Pérez F, Goretzki A, Wolfheimer S, Schülke S (2019): The vaccine adjuvant MPLA activates glycolytic metabolism in mouse mDC by a JNK-dependent activation of mTOR-signaling.
Mol Immunol 106: 159-169.
Online-Abstract

Blanco-Pérez F, Kato Y, Gonzalez-Menendez I, Laiño J, Ohbayashi M, Burggraf M, Krause M, Kirberg J, Iwakura Y, Martella M, Quintanilla-Martinez L, Shibata N, Vieths S, Scheurer S, Toda M (2019): CCR8 leads to eosinophil migration and regulates neutrophil migration in murine allergic enteritis.
Sci Rep 9: 9608.
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Blanco-Pérez F, Papp G, Goretzki A, Möller T, Anzaghe M, Schülke S (2019): Adjuvant Allergen Fusion Proteins as Novel Tools for the Treatment of Type I Allergies.
Arch Immunol Ther Exp (Warsz) 67: 273-293.
Online-Abstract

Jacob T, Vogel L, Reuter A, Wangorsch A, Kring C, Mahler V, Wöhrl BM (2020): Food Processing Does Not Abolish the Allergenicity of the Carrot Allergen Dau c 1: Influence of pH, Temperature, and the Food Matrix.
Mol Nutr Food Res 64: 2000334.
Text

Lin YJ, Anzaghe M, Schülke S (2020): Update on the Pathomechanism, Diagnosis, and Treatment Options for Rheumatoid Arthritis.
Cells 9: E880.
Online-Abstract

Martín-Pedraza L, Wangorsch A, Bueno-Diaz C, De Las Heras M, Scheurer S, Cuesta-Herranz J, Villalba M (2020): 2S Albumins and nsLTP Are Involved in Anaphylaxis to Pizza Sauce: IgE Recognition Before and After Allergen Processing.
Food Chem 321: 126679.
Online-Abstract

Moeller T, Wolfheimer S, Goretzki A, Scheurer S, Schülke S (2019): NFκB- and MAP-Kinase Signaling Contribute to the Activation of Murine Myeloid Dendritic Cells by a Flagellin A: Allergen Fusion Protein.
Cells 8: 355.
Text

Safi H, Wangorsch A, Lidholm J, Brini F, Spiric J, Rihs HP, Vieths S, Armentia A, Farioli L, Diaz-Perales A, Pastorello EA, Scheurer S (2019): Identification and molecular characterization of allergenic nsLTP from durum wheat (Triticum turgidum).
Clin Exp Allergy 49: 120-129.
Online-Abstract

Schülke S, Albrecht M (2019): Mouse Models for Food Allergies: Where Do We Stand?.
Cells 8: 546.
Text

Sliva K, Martin J, von Rhein C, Herrmann T, Weyrich A, Toda M, Schnierle BS (2019): Interference with SAMHD1 Restores Late Gene Expression of Modified Vaccinia Virus Ankara in Human Dendritic Cells and Abrogates Type I Interferon Expression.
J Virol 93: e01097-19.
Text

Toda M, Hellwig M, Henle T, Vieths S (2019): Influence of the Maillard Reaction on the Allergenicity of Food Proteins and the Development of Allergic Inflammation.
Curr Allergy Asthma Rep 19: 4.
Text

Wangorsch A, Kulkarni A, Jamin A, Spiric J, Bräcker J, Brockmeyer J, Mahler V, Blanca-López N, Ferrer M, Blanca M, Torres M, Gomez P, Bartra J, García-Moral A, Goikoetxea MJ, Vieths S, Toda M, Zoccatelli G, Scheurer S (2020): Identification and Characterization of IgE-reactive Proteins and a New Allergen (Cic a 1.01) from Chickpea (Cicer arietinum).
Mol Nutr Food Res 64: e2000560.
Online-Abstract

Yakoub A, Schülke S (2019): A model for apoptotic-mediated adaptive immune evasion via CD80–CTLA-4 signaling.
Front Pharmacol 10: 562.
Online-Abstract

Abteilung Allergologie

Agache I, Annesi-Maesano I, Bonertz A, Branca F, Cant A, Fras Z, Ingenrieth F, Namazova-Baranova L, Odemyr M, Spanevello A, Vieths S, Yorgancioglu A, Alvaro-Lozano M, Barber Hernandez D, Chivato T, Del Giacco S, Diamant Z, Eguiluz-Gracia I, van Wijk RG, Gevaert P, Graessel A, Hellings P, Hoffmann-Sommergruber K, Jutel M, Lau S, Lauerma A, Maria Olaguibel J, O'Mahony L, Ozdemir C, Palomares O, Pfaar O, Sastre J, Scadding G, Schmidt-Weber C, Schmid-Grendelmeier P, Shamji M, Skypala I, Spinola M, Spranger O, Torres M, Vereda A, Bonini S (2019): Prioritizing research challenges and funding for allergy and asthma and the need for translational research - The European Strategic Forum on Allergic Diseases.
Allergy 74: 2064-2076.
Text

Ahrens B: Hydrolysatnahrung.
In: Schäfer T, Reese I (Hrsg.), Allergiepräventation: De Gruyter, 2019. S. 59-72, ISBN 978-3-11-055943-9

Akhras S, Herrlein ML, Elgner F, Holzhauser T, Hildt E (2019): ZIKV Envelope Domain-Specific Antibodies: Production, Purification and Characterization.
Viruses 11: 748.
Text

Allgöwer SM, Hartmann CA, Holzhauser T (2020): The Development of Highly Specific and Sensitive Primers for the Detection of Potentially Allergenic Soybean (Glycine max) Using Loop-Mediated Isothermal Amplification Combined with Lateral Flow Dipstick (LAMP-LFD).
Foods 9: E423.
Text

Allgöwer SM, Hartmann CA, Lipinski C, Mahler V, Randow S, Völker E, Holzhauser T (2020): LAMP-LFD Based on Isothermal Amplification of Multicopy Gene ORF160b: Applicability for Highly Sensitive Low-Tech Screening of Allergenic Soybean (Glycine max) in Food.
Foods 9: E1741.
Online-Abstract

Apfelbacher CJ, Ofenloch RF, Weisshaar E, Molin S, Bauer A, Mahler V, Heinrich A, von Kiedrowski R, Schmitt J, Elsner P, Diepgen TL (2019): Chronic hand eczema in Germany: 5-year follow-up data from the CARPE registry.
Contact Dermatitis 80: 45-53.
Online-Abstract

Aurich S, Spiric J, Engin A, Simon JC, Mahler V (2019): Report of a Case of IgE-Mediated Anaphylaxis to Fenugreek.
J Investig Allergol Clin Immunol 29: 56-58.
Text

Bennike NH, Heisterberg MS, White IR, Mahler V, Silvestre-Salvador JF, Giménez-Arnau A, Johansen JD (2019): Quality of life and disease severity in dermatitis patients with fragrance allergy - A cross-sectional European questionnaire study.
Contact Dermatitis 81: 89-96.
Online-Abstract

Blumchen K, Trendelenburg V, Ahrens F, Gruebl A, Hamelmann E, Hansen G, Heinzmann A, Nemat K, Holzhauser T, Roeder M, Rosenfeld L, Hartmann O, Niggemann B, Beyer K (2019): Efficacy, safety, and quality of life in a multi-center, randomized, placebo-controlled trial of low-dose peanut oral immunotherapy in peanut allergic children.
J Allergy Clin Immunol Pract 7: 479-491.e10.
Online-Abstract

Bonertz A, Mahler V, Vieths S (2020): New guidance on the regulation of allergen products: key aspects and outcomes.
Curr Opin Allergy Clin Immunol 20: 624-630.
Online-Abstract

Bonertz A, Mahler V, Vieths S (2019): Manufacturing and quality assessment of allergenic extracts for immunotherapy: state of the art.
Curr Opin Allergy Clin Immunol 19: 640-645.
Online-Abstract

Costa J, Bavaro SL, Benedé S, Diaz-Perales A, Bueno-Diaz C, Gelencser E, Klueber J, Larré C, Lozano-Ojalvo D, Lupi R, Mafra I, Mazzuchelli G, Molina E, Monaci L, Martin-Petraza L, Piras C, Rodrigues PM, Roncada P, Schrama D, Cirkovic-Velickovic T, Verhoeckx K, Villa C, Kuehn A, Hoffmann-Sommergruber K, Holzhauser T (2020): Are Physicochemical Properties Shaping the Allergenic Potency of Plant Allergens?..
Clin Rev Allergy Immunol Sep 2 [Epub ahead of print].
Online-Abstract

Dickel H, Mahler V (2020): Leitliniengerechte Diagnostik der Kontaktallergie in der Praxis.
Hautarzt 71: 182-189.
Online-Abstract

Erfurt-Berge C, Schmidt A, Angelovska I, Mahler V (2020): Beruflich erworbene MRSA-Besiedelung in der berufsdermatologischen Begutachtung (BK-Nr. 3101): Auswertung der DGUV BK-Dokumentation und Gutachtenfall mit arbeitsbedingter MRSA-getriggerter atopischer Dermatitis.
Hautarzt 71: 1-10.
Text

Ferastraoaru D, Bax HJ, Bergmann C, Capron M, Castells M, Dombrowicz D, Fiebiger E, Gould HJ, Hartmann K, Jappe U, Jordakieva G, Josephs DH, Levi-Schaffer F, Mahler V, Poli A, Rosenstreich D, Roth-Walter F, Shamji M, Steveling-Klein EH, Turner MC , Untersmayr E, Karagiannis SN, Jensen-Jarolim E (2020): AllergoOncology: ultra-low IgE, a potential novel biomarker in cancer-a Position Paper of the European Academy of Allergy and Clinical Immunology (EAACI).
Clin Transl Allergy 10: 32.
Text

Fiedler SA, Boller K, Junker AC, Kamp C, Hilger A, Schwarz W, Seitz R, Salge-Bartels U (2020): Evaluation of the in vitro function of platelet concentrates from pooled buffy coats or apheresis.
Transfus Med Hemother 47: 314-324.
Text

Geier J, Lessmann H, Bauer A, Becker D, Dickel H, Fartasch M, Häberle M, John SM, Krohn S, Mahler V, Skudlik C, Weisshaar E, Werfel T, Diepgen TL (2019): Auswirkung einer arbeitsbedingten Kontaktallergie gegen Propylenglykol bei der BK 5101.
Dermatologie in Beruf und Umwelt 67: 27-31.
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Geier J, Mahler V (2019): Das kleine 1x1 der Kontaktallergene - Teil 18: Konservierungsmittel.
Allergo J 28: 18-21.
Text

Holzhauser T, Johnson P, Hindley JP, O'Connor G, Chan CH, Costa J, Fæste CK, Hirst BJ, Lambertini F, Miani M, Robert MC, Röder M, Ronsmans S, Bugyi Z, Tömösközi S, Flanagan SD (2020): Are current analytical methods suitable to verify VITAL® 2.0/3.0 Allergen Reference doses for EU Allergens in Foods?.
Food Chem Toxicol 145: 111709.
Online-Abstract

Holzhauser T, Schuler F, Dudek S, Kaul S, Vieths S, Mahler V (2020): Rekombinante Allergene, Peptid und Virus-like Particles in der Immuntherapie von Allergien.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1412-1423.
Online-Abstract

Horton E, Uter W, Geier J, Ballmer-Weber B, Bauer A, Bircher A, Dickel H, Giménez-Arnau A, Goncalo M, John SM, Mahler V, Schuttelaar MLA, Simon D, Sanchez-Perez J, Rustemeyer T, Weisshaar E, Wilkinson SM (2020): Developing a cosmetic series: results from the ESSCA network, 2009-2018.
Contact Dermatitis 84: 82-94.
Online-Abstract

Jacob T, von Loetzen CS, Reuter A, Lacher U, Schiller D, Schobert R, Mahler V, Vieths S, Rösch P, Schweimer K, Wöhrl BM (2019): Identification of a natural ligand of the hazel allergen Cor a 1.
Sci Rep 9: 8714.
Text

Jacob T, Vogel L, Reuter A, Wangorsch A, Kring C, Mahler V, Wöhrl BM (2020): Food Processing Does Not Abolish the Allergenicity of the Carrot Allergen Dau c 1: Influence of pH, Temperature, and the Food Matrix.
Mol Nutr Food Res 64: 2000334.
Text

Jensen-Jarolim E, Bachmann M, Bonini S, Jacobsen L, Jutel M, Klimek L, Mahler V, Mösges R, Moingeon P, O Hehir RE, Palomares O, Pfaar O, Renz H, Rhyner C, Roth-Walter F, Rudenko M, Savolainen J, Schmidt-Weber C, Traidl-Hoffmann C, Kündig T (2020): State-of-the-art in marketed adjuvants and formulations in Allergen Immunotherapy: a position paper of the European Academy of Allergy and Clinical Immunology (EAACI).
Allergy 75: 746-760.
Online-Abstract

Kleine-Tebbe J, Kaul S, Mösges R (2019): Allergen immunotherapy phase II trials: Challenges in dose finding.
Allergol Select 3: 1-8.
Online-Abstract

Klimek L, Hoffmann HJ, Kalpaklioglu AF, Demoly P, Agache L, Popov T, Muraro A, Schmid-Grendelmeier P, Bonini S, Bonertz A, Mahler V, Vieths S, Pfaar O, Zuberbier T, Jutel M, Schmidt-Weber C, Hellings P, Dreborg S, Bonini M, Brough HA, Bousquet J, Hoffmann-Sommergruber K, Palomares O, Ollert M, Shamji MH, Cardona V (2020): In-vivo Diagnostic Test Allergens in Europe: A Call to Action and Proposal for Recovery Plan - An EAACI Position Paper.
Allergy 75: 2161-2169.
Online-Abstract

Klueber J, Costa J, Randow S, Codreanu-Morel F, Verhoeckx K, Bindslev-Jensen C, Ollert M, Hoffmann-Sommergruber K, Morisset M, Holzhauser T, Kuehn A (2019): Homologous tropomyosins from vertebrate and invertebrate: Recombinant calibrator proteins in functional biological assays for tropomyosin allergenicity assessment of novel animal foods.
Clin Exp Allergy 50: 105-116.
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Kraft M, Knop MP, Renaudin JM, Scherer Hofmeier K, Pföhler C, Biló MB, Lang R, Treudler R, Wagner N, Spindler T, Hourihane JO, Maris I, Koehli A, Bauer A, Lange L, Müller S, Papadopoulos NG, Wedi B, Moeser A, Ensina LF, Fernandez-Rivas M, Cichocka-Jarosz E, Christoff G, Garcia BE, Poziomkowska-Gesicka I, Cardona V, Mustakov TB, Rabe U, Mahler V, Grabenhenrich L, Dölle-Bierke S, Worm M, Network for Online Registration of Anaphylaxis (NORA) (2020): Secondary prevention measures in anaphylaxis patients: Data from the anaphylaxis registry.
Allergy 75: 901-910.
Text

Lázaro-Gorines R, López-Rodriguez JC, Benedé S, González M, Mayorga C, Vogel L, Martinez-del-Pozo Á, Lacadena J, Villalba M (2020): Der p 1-based immunotoxin as potential tool for the treatment of dust mite respiratory allergy.
Sci Rep 10: 12255.
Text

Mahler V (2019): Testallergene: Aktueller Stand der Verfügbarkeit aus regulatorischer Sicht.
Allergologie 42: 309-313.
Online-Abstract

Mahler V, Bonertz A, Ruoff C, Hartenstein D, Mentzer D, Kaul S, Vieths S (2019): What we learned from TAO - 10 years of German therapy allergen ordinance.
Allergo J Int 28: 330-337.
Online-Abstract

Mahler V, Dickel H (2019): Wichtigste Kontaktallergene beim Handekzem.
Hautarzt 70: 778-789.
Online-Abstract

Mahler V: Topical Corticosteroids.
EAACI Global Atlas of Skin Allergy, 2019. S. 240-243
(Section H - Management of skin allergic diseases)

Mahler V, Esch RE, Kleine-Tebbe J, Lavery WJ, Plunkett G, Vieths S, Bernstein DI (2019): Understanding Differences in Allergen Immunotherapy Products and Practices in North America and Europe.
J Allergy Clin Immunol 143: 813-828.
Text

Mahler V (2019): Nachgefragt - Bei Epikutantests gibt es viele Fehlerquellen.
hautnah dermatologie 35: 56.
Text

Mahler V, Kleine-Tebbe J, Vieths S (2020): Immuntherapien von Allergien: Aktueller Stand.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1341-1356.
Online-Abstract

Mahler V (2020): Allergische Rhinitis: Zugang zu Allergen-Immuntherapie erleichtert.
Kompass Dermatol 8: 107-108.
Online-Abstract

Mahler V (2019): Neue Charakteristika klinisch manifester Latexallergiker.
Kompass Dermatol 7: 29-31.
Online-Abstract

Mahler V (2019): Präventionskonzepte für Nahrungsmittelallergien im Wandel.
Kompass Dermatol 7: 123-125.
Online-Abstract

Mahler V, Mentzer D, Bonertz A, Muraro A, Eigenmann P, Bousquet J, Halken S, Pfaar O, Jutel M, Wahn U, Vieths S, Kaul S (2020): Allergen Immunotherapy (AIT) in children: a vulnerable population with its own rights and legislation - summary of EMA-initiated multi-stakeholder meeting on Allergen Immunotherapy (AIT) for children, held at Paul-Ehrlich-Institut, Langen, Germany, 16.1.2019.
Clin Transl Allergy 10: 28.
Text

Mahler V, Nast A, Bauer A, Becker D, Brasch J, Breuer K, Dickel H, Drexler H, Elsner P, Geier J, John SM, Kreft B, Köllner A, Merk H, Ott H, Pleschka S, Portisch M, Spornraft-Ragaller P, Weisshaar E, Werfel T, Worm M, Schnuch A, Uter W (2019): S3-Leitlinie: Durchführung des Epikutantests mit Kontaktallergenen und Arzneimitteln - Kurzfassung Teil 2.
J Dtsch Dermatol Ges 17: 1187-1207.
Online-Abstract

Mahler V, Nast A, Bauer A, Becker D, Brasch J, Breuer K, Dickel H, Drexler H, Elsner P, Geier J, John SM, Kreft B, Köllner A, Merk H, Ott H, Pleschka S, Portisch M, Spornraft-Ragaller P, Weisshaar E, Werfel T, Worm M, Schnuch A, Uter W (2019): S3-Leitlinie: Durchführung des Epikutantests mit Kontaktallergenen und Arzneimitteln - Kurzfassung Teil 1.
J Dtsch Dermatol Ges 17: 1075-1093.
Online-Abstract

Mahler V, Nast A, Uter W (2019): Methodenreport der S3‐Leitlinie zur "Durchführung des Epikutantests mit Kontaktallergenen und Arzneimitteln".
J Dtsch Dermatol Ges Nov 26 [Epub ahead of print].
Online-Abstract

Mahler V, Zielen S, Rosewich M (2019): Year-round treatment initiation for a 6-grasses pollen allergoid in specific immunotherapy of allergic rhinoconjunctivitis and asthma.
Immunotherapy 11: 1569-1582.
Online-Abstract

Moritz CP, Mühlhaus T, Tenzer S, Schulenborg T, Friauf E (2019): Poor transcript-protein correlation in the brain: negatively correlating gene products reveal neuronal polarity as a potential cause.
J Neurochem 149: 582-604.
Online-Abstract

Oeo-Santos C, Navas A, Benedé S, Ruíz-León B, Díaz-Perales A, Vogel L, Moreno-Aguilar C, Jurado A, Villalba M, Barderas R (2020): New insights into the sensitization to nonspecific lipid transfer proteins from pollen and food: New role of allergen Ole e 7.
Allergy 75: 798-807.
Online-Abstract

Oosterhaven JAF, Uter W, Aberer W, Armario-Hita JC, Ballmer-Weber BK, Bauer A, Czarnecka-Operacz M, Elsner P, García-Gavín J, Giménez-Arnau AM, John SM, Krecisz B, Mahler V, Rustemeyer T, Sadowska-Przytocka A, Sanchez-Perez J, Simon D, Valiukeviciene S, Weisshaar E, Schuttelaar MLA, ESSCA Working Group (2019): European Surveillance System on Contact Allergies (ESSCA): contact allergies in relation to body sites in patients with allergic contact dermatitis.
Contact Dermatitis 80: 263-272.
Online-Abstract

Pfaar O, Agache I, Bergmann KC, Bindslev-Jensen C, Bousquet J, Creticos PS, Devillier P, Durham SR, Hellings P, Kaul S, Kleine-Tebbe J, Klimek L, Jacobsen L, Jutel M, Muraro A, Papadopoulos NG, Rief W, Scadding GK, Schedlowski M, Shamji MH, Sturm G, van Ree R, Vidal C, Vieths S, Wedi B, Gerth van Wijk R, Frew AJ (2020): Placebo Effects in Allergen Immunotherapy - An EAACI Task Force Position Paper.
Allergy 76: 629-647.
Online-Abstract

Popp J, Trendelenburg V, Niggemann B, Randow S, Völker E, Vogel L, Reuter A, Spiric J, Schiller D, Beyer K, Holzhauser T (2020): Pea (Pisum sativum) allergy in children: Pis s 1 is an immunodominant major pea allergen and presents IgE binding sites with potential diagnostic value.
Clin Exp Allergy 50: 625-635.
Online-Abstract

Reese I, Schäfer C, Kleine-Tebbe J, Ahrens B, Bachmann O, Ballmer-Weber B, Beyer K, Bischoff SC, Blümchen K, Dölle S, Enck P, Enninger A, Huttegger I, Lämmel S, Lange L, Lepp U, Mahler V, Mönnikes H, Ockenga J, Otto B, Schnadt S, Szepfalusi Z, Treudler R, Wassmann-Otto A, Zuberbier T, Werfel T, Worm M (2019): Nicht-Zöliakie-Gluten-/Weizen-Sensitivität (NCGS) – ein bislang nicht definiertes Krankheitsbild mit fehlenden Diagnosekriterien und unbekannter Häufigkeit.
Allergologie 42: 111-117.
Online-Abstract

Rosti B, Mahler V (2020): Adding a Second Skin Prick Test Reading and Modifying the Cut-off for Beta-lactam-specific IgE Enhances the Sensitivity in the Routine Diagnostic Work-Up for Immediate Beta-lactam-hypersensitivity.
Contact Dermatitis 83: 361-371.
Online-Abstract

Safi H, Wangorsch A, Lidholm J, Brini F, Spiric J, Rihs HP, Vieths S, Armentia A, Farioli L, Diaz-Perales A, Pastorello EA, Scheurer S (2019): Identification and molecular characterization of allergenic nsLTP from durum wheat (Triticum turgidum).
Clin Exp Allergy 49: 120-129.
Online-Abstract

Schubert S, Brans R, Reich A, Buhl A, Skudlik C, Schröder-Kraft C, Gina M, Weisshaar E, Mahler V, Dickel H, Schön MP, John SM, Geier J, IVDK (2020): Contact sensitization in metalworkers: data from the Information Network of Departments of Dermatology (IVDK), 2010 - 2018.
Contact Dermatitis 83: 487-496.
Online-Abstract

Seutter von Loetzen C, Reuter A, Spiric J, Schulenborg T, Bellinghausen I, Völker E, Vogel L, Rösch P, Schiller D (2019): Quality and potency profile of eight recombinant isoallergens, largely mimicking total Bet v 1-specific IgE binding of birch pollen.
Clin Exp Allergy 49: 712-723.
Online-Abstract

Singh S, Akhter MS, Dodt J, Volkers P, Reuter A, Reinhart C, Krettler C, Oldenburg J, Biswas A (2019): Identification of Potential Novel Interacting Partners for Coagulation Factor XIII B (FXIII-B) Subunit, a Protein Associated with a Rare Bleeding Disorder.
Int J Mol Sci 20: 2682.
Online-Abstract

Süß H, Dölle-Bierke S, Geier J, Kreft B, Oppel E, Pföhler C, Skudlik C, Worm M, Mahler V (2019): Contact urticaria: Frequency, elicitors and cofactors in three cohorts (Information Network of Departments of Dermatology; Network of Anaphylaxis; and Department of Dermatology, University Hospital Erlangen, Germany).
Contact Dermatitis 81: 341-353.
Text

Trendelenburg V, Blumchen K, Bellach J, Ahrens F, Gruebl A, Hamelmann E, Hansen G, Heinzmann A, Nemat K, Holzhauser T, Röder M, Niggemann B, Beyer K (2020): Peanut oral immunotherapy protects patients from accidental allergic reactions to peanut.
J Allergy Clin Immunol Pract 8: 2437-2441.e3.
Online-Abstract

Trösemeier JH, Rudorf S, Loessner H, Hofner B, Reuter A, Schulenborg T, Koch I, Bekeredjian-Ding I, Lipowsky R, Kamp C (2019): Optimizing the dynamics of protein expression.
Sci Rep 9: 7511.
Text

Uter W, Bauer A, Belloni Fortina A, Bircher AJ, Brans R, Buhl T, Cooper SM, Czarnecka-Operacz M, Dickel H, Dugonik A, Geier J, Giménez-Arnau AM, Goncalo M, Johansen JD, Johnston GA, Mahler V, Rustemeyer T, Sanchez-Perez J, Schuttelaar MLA, Simon D, Spiewak R, Valiukevicien S, Weisshaar E, White IR, Wilkinson M, ESSCA working group (2021): Patch test results with the European baseline series and additions thereof in the ESSCA network, 2015-2018.
Contact Dermatitis 84: 109-120.
Online-Abstract

Uter W, Gefeller O, Mahler V, Geier J (2020): Trends and Current Spectrum of Contact Allergy in Central Europe: Results of the Information Network of Departments of Dermatology (IVDK) 2007-2018.
Br J Dermatol 183: 857-865.
Online-Abstract

Verhoeckx K, Lindholm Bøgh K, Constable A, Epstein M, Hoffmann-Sommergruber K, Holzhauser T, Houben G, Kuehn A, Roggen E, O'Mahony L, Remington B, Crevel R (2020): COST Action ‘ImpARAS’: what have we learnt to improve food allergy risk assessment. A summary of a 4 year networking consortium.
Clin Transl Allergy 10: 13.
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Walter C, Ott H, Ahrens B (2019): Urtikaria - Ein Vorschlag zur Umsetzung der aktuell überarbeiteten europäischen Leitlinie in die pädiatrische Praxis.
Pädiatrische Allergologie 2019: 4-11.
Text

Wangorsch A, Kulkarni A, Jamin A, Spiric J, Bräcker J, Brockmeyer J, Mahler V, Blanca-López N, Ferrer M, Blanca M, Torres M, Gomez P, Bartra J, García-Moral A, Goikoetxea MJ, Vieths S, Toda M, Zoccatelli G, Scheurer S (2020): Identification and Characterization of IgE-reactive Proteins and a New Allergen (Cic a 1.01) from Chickpea (Cicer arietinum).
Mol Nutr Food Res 64: e2000560.
Online-Abstract

Whitehouse H, Uter W, Geier J, Ballmer-Weber B, Bauer A, Cooper S, Czarnecka-Operacz M, Dagmar S, Dickel H, Belloni Fortina A, Gallo R, Giménez-Arnau AM, Johnston GA, Laresse Filon F, Mahler V, Pesonen M, Rustemeyer T, Schuttelaar MLA, Valiukevičien S, Weisshaar E, Werfel T, Wilkinson SM (2021): Formaldehyde 2% is not a useful means of detecting allergy to formaldehyde releasers- results of the ESSCA network, 2015 - 2018.
Contact Dermatitis 84: 95-102.
Online-Abstract

Wilkinson M, Goncalo M, Aerts O, Badulici S, Bennike NH, Bruynzeel D, Dickel H, Garcia-Abujeta JL, Gimenez-Arnau AM, Hamman C, Isaksson M, Johansen JD, Mahler V, Niklasson B, Orton D, Pigatto P, Ponyai G, Rustemeyer T, Schuttelaar MLA, Spiewak R, Thyssen JP, Uter W (2019): The European baseline series and recommended additions: 2019.
Contact Dermatitis 80: 1-4.

Wurpts G, Aberer W, Dickel H, Brehler R, Jakob T, Kreft B, Mahler V, Merk HF, Mülleneisen N, Ott H, Pfützner W, Röseler S, Rueff F, Sitter H, Sunderkötter C, Trautmann A, Treudler R, Wedi B, Worm M, Brockow K (2020): Guideline on diagnostic procedures for suspected hypersensitivity to beta-lactam antibiotics: Guideline of the German Society for Allergology and Clinical Immunology (DGAKI) in collaboration with the German Society of Allergology (AeDA), German Society for Pediatric Allergology and Environmental Medicine (GPA), the German Contact Dermatitis Research Group (DKG), the Austrian Society for Allergology and Immunology (ÖGAI), and the Paul-Ehrlich Society for Chemotherapy (PEG).
Allergol Select 4: 11-43.
Text

Zahn T, Akhras S, Spengler C, Murra RO, Holzhauser T, Hildt E (2020): A new approach for therapeutic vaccination against chronic HBV infections.
Vaccine 38: 3105-3120.
Online-Abstract

Abteilung Grundsatzfragen, Koordination

Baylis SA, Wallace P, McCulloch E, Niesters HGM, Nübling CM (2019): Standardization of nucleic acid amplification tests: the approach of the World Health Organization.
J Clin Microbiol 57: e01056-18.
Online-Abstract

Kafere C, Tayou Tagny C, Tapko JB, Mbunkah HA, Samukange WT, Mutoti K, Mudyiwenyama L, Sumaila A, Reinhardt J (2020): Congress Report: Implementation of Blood and Blood Product Regulation Training Workshop, South Africa.
Africa Sanguine 22: 5-9.
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Kempster SL, Almond N, Dimech W, Grangeot-Keros L, Huzly D, Icenogle J, Sittana El Mubarak H, Mulders MN, Nübling M (2020): WHO international standard for anti-rubella: learning from its application.
Lancet Infect Dis 20: E17-E19.
Online-Abstract

Kress J, Vermeulen M, Chudy M, Reissinger A, Hanschmann KM, Saville A, Nübling CM (2020): Reliability of CE-marked NATs for HIV-1 subtype C detection and quantitation.
J Clin Virol 132: 104649.
Online-Abstract

Mbunkah HA, Bertagnolio S, Hamers RL, Hunt G, Inzaule S, Rinke de Wit TF, Paredes R, Parkin NT, Jordan MR, Metzner KJ, WHO HIVResNetWorking Group (2020): Low-Abundance Drug-Resistant HIV-1 Variants in Antiretroviral Drug-Naive Individuals: A Systematic Review of Detection Methods, Prevalence, and Clinical Impact.
J Infect Dis 221: 1584-1597.
Online-Abstract

Mbunkah HA, Reinhardt J, Kafere C, Scheiblauer H, Prat I, Nübling CM (2021): In vitro diagnostics for screening the blood supply: the new European regulation for IVD and the WHO IVD prequalification programme.
Vox Sang 116: 3-12.
Text

Müller-Berghaus J, Sarac SB, Schüssler-Lenz M (2020): Kombinationstherapien in der Immunonkologie: Differenzierte regulatorische Herangehensweisen.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1388-1395.
Online-Abstract

Ovanesov MV, Williams SC, Nübling CM, Dodt J, Hilger A, Maryuningsih Y, Gray E (2020): Summary of the WHO hearing on the development of product-specific reference materials for coagulation factor VIII and factor IX products.
Biologicals 67: 88-93.
Online-Abstract

Papadouli I, Mueller-Berghaus J, Beuneu C, Ali S, Hofner B, Petavy F, Tzogani K, Miermont A, Norga K, Kholmanskikh O, Leest T, Schuessler-Lenz M, Salmonson T, Gisselbrecht C, Garcia JL, Pignatti F (2020): EMA Review of Axicabtagene Ciloleucel (Yescarta) for the Treatment of Diffuse Large B-Cell Lymphoma.
Oncologist 25: 894-902.
Online-Abstract

Pinz A, Altrichter-Dünnes S, Ateba Ngoa U, Atemnkeng J, Heinrich K, Conrad C, Reinhardt J (2020): E-learning approach for capacity building in the area of regulatory systems strengthening in Africa.
Transfus Med Hemother 47: 13.
Online-Abstract

Reul J, Muik A, Buchholz CJ (2019): Ligand Coupling to the AAV Capsid for Cell-Specific Gene Transfer.
Methods Mol Biol 1950: 35-50.
Online-Abstract

Samukange WT, Gardarsdottir H, Leufkens HGM, Mantel-Teeuwisse AK (2020): Selection of Blood, Blood Components, and Blood Products as Essential Medicines in 105 Low- and Middle-Income Countries.
Transfus Med Rev 34: 94-100.
Online-Abstract

Samukange WT, Klümpers V, Kafere C, Schuler F, Tirane FJ, Kabaso B, Chama D, Ejeh EA, Reinhardt J (2020): Report from the GHPP-BloodTrain inspection workshop in Harare the 20th to the 24th of May 2019.
Biologicals 68: 125-128.
Online-Abstract

Sekyere SO, Port K, Deterding K, Cornberg M, Wedemeyer H (2020): Inflammatory patterns in plasma associate with hepatocellular carcinoma development in cured hepatitis C cirrhotic patients.
United European Gastroenterol J Dec 21 [Epub ahead of print].
Online-Abstract

Sheets R, Kang HN, Meyer H, Knezevic I, and WHO informal consultation on development of guidelines for assuring the quality, safety, and efficacy of DNA vaccine (2020): WHO Informal Consultation on the Guidelines for Evaluation of the Quality, Safety, and Efficacy of DNA Vaccines, Geneva, Switzerland, December 2019.
NPJ Vaccines 5: 52.
Text

Škrnjug I, Uzeirbegović S, Romčević ML, Tomić S, Meyer H, Conrad C (2019): Mutual recognition in the European system: A blueprint for increasing access to medicines?.
Regul Toxicol Pharmacol 106: 270-277.
Text

Vermeer NS, Giezen TJ, Zastavnik S, Wolff-Holz E, Hidalgo-Simon A (2019): Identifiability of biologicals in adverse drug reaction reports received from European clinical practice.
Clin Pharmacol Ther 105: 962-969.
Online-Abstract

Wenk BM, Mbunkah HA, Nsanwe NN, Mbu ET, Besong LM, Sama BA, Orock E, Leemann C, Mentzer KJ (2021): Prevalence of integrase strand transfer inhibitor resistance mutations in antiretroviral-naive HIV-1-infected individuals in Cameroon.
J Antimicrob Chemother 76: 124-129.
Online-Abstract

Wolff-Holz E, Müller-Berghaus J, Weise M (2019): Biosimilars in der Onkologie (Teil 1): Dank strenger Regulierung keine zweite Wahl.
Dtsch Arztebl 116: 28-34.
Online-Abstract

Wolff-Holz E, Müller-Berghaus J, Weise M (2019): Biosimilars in der Onkologie (Teil 2): Wie man die Biosimilarität wissenschaftlich bestätigt.
Dtsch Arztebl 116: 14-19.
Online-Abstract

Wolff-Holz E, Tiitso K, Vleminckcx C, Weise M (2019): Evolution of the EU Biosimilar Framework: Past and Future.
BioDrugs 33: 621-634.
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Wolff-Holz E, Weise M (2020): Biosimilars in der EU: Bestandsaufnahme und neue Herausforderungen.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1365-1372.
Online-Abstract

Abteilung Hämatologie / Transfusionsmedizin

Byskov K, Etscheid M, Kanse SM (2020): Cellular Effects of Factor VII Activating Protease (FSAP).
Thromb Res 188: 74-78.
Online-Abstract

Domanovic D, Gossner CM, Lieshout-Krikke R, Mayr W, Baroti-Toth K, Dobrota AM, Escoval MA, Henseler O, Jungbauer C, Liumbruno G, Oyonarte S, Politis C, Sandid I, Stojic Vidovic M, Young JJ, Ushiro-Lumb I, Nowotny N (2019): West Nile and Usutu Virus Infections and Challenges to Blood Safety in the European Union.
Emerg Infect Dis 25: 1050-1057.
Text

Duda H, Hesse J, Haschberger B, Hilger A, Keipert C (2020): The German Hemophilia Registry: Growing with Its Tasks.
J Clin Med 9: E3408.
Online-Abstract

Eichler H, Feyer AK, Weitmann K, Hoffmann W, Henseler O, Opitz A, Patek A, Hans DN, Schönborn L, Greinacher A (2020): Population-Based Analysis of the Impact of Demographics on the Current and Future Blood Supply in the Saarland.
Transfus Med Hemother Dec 23 [Epub ahead of print].
Online-Abstract

Fiedler SA, Boller K, Junker AC, Kamp C, Hilger A, Schwarz W, Seitz R, Salge-Bartels U (2020): Evaluation of the in vitro function of platelet concentrates from pooled buffy coats or apheresis.
Transfus Med Hemother 47: 314-324.
Text

Fiedler SA, Oberle D, Chudy M, Scheiblauer H, Henseler O, Halbauer J, Heiden M, Funk MB (2019): Effectiveness of blood donor screening by HIV, HCV, HBV‐NAT assays, as well as HBsAg and anti‐HBc immunoassays in Germany (2008–2015).
Vox Sang 114: 443-450.
Online-Abstract

Kafere C, Tayou Tagny C, Tapko JB, Mbunkah HA, Samukange WT, Mutoti K, Mudyiwenyama L, Sumaila A, Reinhardt J (2020): Congress Report: Implementation of Blood and Blood Product Regulation Training Workshop, South Africa.
Africa Sanguine 22: 5-9.
Text

Karamloo F, König R (2020): SARS-CoV-2 immunogenicity at the crossroads.
Allergy 75: 1822-1824.
Online-Abstract

Keipert C, Müller-Olling M, Gauly F, Arras-Reiter C, Hilger A (2020): Annual Bleeding Rates: Pitfalls of Clinical Trial Outcomes in Hemophilia Patients.
Clin Transl Sci 13: 1127-1136.
Text

Konkle BA, Recht M, Hilger A, Marks P (2021): The critical need for postmarketing surveillance in gene therapy for haemophilia.
Haemophilia 27: 126-131.
Text

Mbunkah HA, Reinhardt J, Kafere C, Scheiblauer H, Prat I, Nübling CM (2021): In vitro diagnostics for screening the blood supply: the new European regulation for IVD and the WHO IVD prequalification programme.
Vox Sang 116: 3-12.
Text

Nielsen NV, Roedel E, Manna D, Etscheid M, Morth JP, Kanse SM (2019): Characterization of the enzymatic activity of the serine protease domain of Factor VII activating protease (FSAP).
Sci Rep 9: 18990.
Text

Ovanesov MV, Williams SC, Nübling CM, Dodt J, Hilger A, Maryuningsih Y, Gray E (2020): Summary of the WHO hearing on the development of product-specific reference materials for coagulation factor VIII and factor IX products.
Biologicals 67: 88-93.
Online-Abstract

Peyvandi F, Berger K, Seitz R, Hilger A, Hecquet ML, Wierer M, Buchheit KH, O'Mahony B, Bok A, Makris M, Mansmann U, Schramm W, Mannucci PM (2020): Kreuth V initiative: European consensus proposals for treatment of hemophilia using standard products, extended half-life coagulation factor concentrates and non-replacement therapies.
Haemotologica 105: 2038-2043.
Text

Pierce GF, Coffin D, Members of the WFH Gene Therapy Round Table Program Committee and Orgazining Committee, Lillicrap D, Ozelo M, Pasi J, Rotellini D, Marquez S, Sannié T, Srivastava A, den Berg M, Weill A, Almeida A, Baumann A, Brooker M, Durante L, Naccache M, Robinson F, Bagley L, Chapin J, Diop S, El Ekiaby M, Flume M, George L, Grehan J, Hawe M, High K, Hilger A, Jonsson B, Kim J, Kimmelman J, Kobelt G, Lee M, Lillicrap D, Linares A, Lozier J, Mahlangu J, Makris M, Marten K, Mathew P, Noone D, O'Hara J, Ozelo M, Ohmori T, Page D, Pasi J, Perry J, Pierce G, Hernandez P, Ragni M, Rakha M, Rayner B, Reiss U, Rollmann D, Rotellini D, Ruff P, Ruiz S, Marquez S, Sannié T, Sathyanarayanan R, Skinner M, Srivastava A, Tortella B, Tuddenham E, Valentino L, den Berg M, Vandendriessche T, Weill A, Yang R, Zelenkofske S (2019): The 1st WFH Gene Therapy Round Table: Understanding the landscape and challenges of gene therapy for haemophilia around the world.
Haemophilia 25: 189-194.
Text

Pinz A, Altrichter-Dünnes S, Ateba Ngoa U, Atemnkeng J, Heinrich K, Conrad C, Reinhardt J (2020): E-learning approach for capacity building in the area of regulatory systems strengthening in Africa.
Transfus Med Hemother 47: 13.
Online-Abstract

Samukange WT, Klümpers V, Kafere C, Schuler F, Tirane FJ, Kabaso B, Chama D, Ejeh EA, Reinhardt J (2020): Report from the GHPP-BloodTrain inspection workshop in Harare the 20th to the 24th of May 2019.
Biologicals 68: 125-128.
Online-Abstract

Schramm W, Seitz R, Gürtler L (2020): COVID-19-associated coagulopathy - Hypothesis: Are Children protected due to enhanced thrombin inhibition by higher α2 -Macroglobulin (α2-M)?.
J Thromb Haemost 18: 2416-2418.
Online-Abstract

Seenivasan R, Hermanns T, Blyszcz T, Lammers M, Praefcke GJK, Hofmann K (2019): Mechanism and chain specificity of RNF216/TRIAD3, the ubiquitin ligase mutated in Gordon Holmes syndrome.
Hum Mol Genet 28: 2862-2873.
Online-Abstract

Seitz R, Gürtler L, Schramm W (2021): Thromboinflammation in COVID-19: Can α2-Macroglobulin Help to Control the Fire?.
J Thromb Haemost 19: 351-354.
Online-Abstract

Seitz R, Schramm W (2020): DIC in COVID-19: Implications for Prognosis and Treatment?.
J Thromb Haemost 18: 1798-1799.
Online-Abstract

Singh S, Akhter MS, Dodt J, Sharma A, Kaniyappan S, Yadegari H, Ivaskevicius V, Oldenburg J, Biswas A (2019): Disruption of Structural Disulfides of Coagulation FXIII-B Subunit; Functional Implications for a Rare Bleeding Disorder.
Int J Mol Sci 20: 1956.
Text

Singh S, Akhter MS, Dodt J, Volkers P, Reuter A, Reinhart C, Krettler C, Oldenburg J, Biswas A (2019): Identification of Potential Novel Interacting Partners for Coagulation Factor XIII B (FXIII-B) Subunit, a Protein Associated with a Rare Bleeding Disorder.
Int J Mol Sci 20: 2682.
Online-Abstract

Singh S, Dodt J, Volkers P, Hethershaw E, Philippou H, Ivaskevicius V, Imhof D, Oldenburg J, Biswas A (2019): Structure functional insights into calcium binding during the activation of coagulation factor XIII A.
Sci Rep 9: 11324.
Online-Abstract

Sriramachandran AM, Meyer-Teschendorf K, Pabst S, Ulrich HD, Gehring NH, Hofmann K, Praefcke GJK, Dohmen RJ (2019): Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain.
Nat Commun 10: 3678.
Online-Abstract

Abteilung Immunologie

Anzaghe M, Resch T, Schaser E, Kronhart S, Diez C, Niles MA, Korotkova E, Schülke S, Wolfheimer S, Kreuz D, Wingerter M, Bartolomé Rodríguez MM, Waibler Z (2019): Organ-specific expression of IL-1 receptor results in severe liver injury in type I interferon receptor deficient mice.
Front Immunol 10: 1009.
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Blanco-Pérez F, Kato Y, Gonzalez-Menendez I, Laiño J, Ohbayashi M, Burggraf M, Krause M, Kirberg J, Iwakura Y, Martella M, Quintanilla-Martinez L, Shibata N, Vieths S, Scheurer S, Toda M (2019): CCR8 leads to eosinophil migration and regulates neutrophil migration in murine allergic enteritis.
Sci Rep 9: 9608.
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Borst K, Flindt S, Blank P, Larsen PK, Chhatbar C, Skerra J, Spanier J, Hirche C, König M, Alanentalo T, Hafner M, Waibler Z, Pfeffer K, Sexl V, Sutter G, Müller W, Graalmann T, Kalinke U (2020): Selective reconstitution of IFN‑γ gene function in Ncr1+ NK cells is sufficient to control systemic vaccinia virus infection.
PLoS Pathog 16: e1008279.
Online-Abstract

Chan KH, Petrychenko V, Mueller C, Maracci C, Holtkamp W, Wilson DN, Fischer N, Rodnina MV (2020): Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun 11: 4106.
Text

Chanyalew M, Abebe M, Endale B, Girma S, Tasew G, van Zandbergen G, Ritter U, Gadisa E, Aseffa A, Laskay T (2020): Enhanced production of pro-inflammatory cytokines and chemokines in Ethiopian cutaneous leishmaniasis upon exposure to Leishmania aethiopica.
Cytokine 18: 155289.
Online-Abstract

Crauwels P, Bank E, Walber B, Wenzel UA, Agerberth B, Negatue MC, Alemayehu MA, König R, Ritter U, Reiling N, van Zandbergen G (2019): Cathelicidin mediated elimination of Leishmania in human host macrophages.
Front Immunol 10: 2697.
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Dudek S, Weißmüller S, Anzaghe M, Miller L, Sterr S, Hoffmann K, Hengel H, Waibler Z (2019): Human Fcγ receptors compete for TGN1412 binding which determines the antibody's effector function.
Eur J Immunol 49: 1117-1126.
Online-Abstract

Fiedler SA, Boller K, Junker AC, Kamp C, Hilger A, Schwarz W, Seitz R, Salge-Bartels U (2020): Evaluation of the in vitro function of platelet concentrates from pooled buffy coats or apheresis.
Transfus Med Hemother 47: 314-324.
Text

Finke J, Hitschler L, Boller K, Florin L, Lang T (2020): HPV caught in the tetraspanin web?.
Med Microbiol Immunol 209: 447-459.
Text

Godehardt AW, Fischer N, Rauch P, Gulich B, Boller K, Church GM, Tönjes RR (2020): Characterization of porcine endogenous retrovirus particles released by the CRISPR/Cas9 inactivated cell line PK15 clone 15.
Xenotransplantation 27: e12563.
Online-Abstract

Gurwith M, Condit RC, Excler JL, Robertson JS, Kim D, Fast PE, Drew S, Wood D, Klug B, Whelan M, Mallett Moore T, Khuri-Bulos N, Smith ER, Chen RT, Kochhar S, Brighton Collaboration Viral Vector Vaccines Safety Working Group V3SWG (2020): Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) standardized template for collection of key information for benefit-risk assessment of live-attenuated viral vaccines.
Vaccine 38: 7702-7707.
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Jiang B, Wen X, Wu Q, Bender D, Carra G, Basic M, Kubesch A, Peiffer KH, Boller K, Hildt E (2020): The N-Terminus Makes the Difference: Impact of Genotype-Specific Disparities in the N-Terminal Part of The Hepatitis B Virus Large Surface Protein on Morphogenesis of Viral and Subviral Particles.
Cells 9: E1898.
Online-Abstract

Jiang B, Wu Q, Kuhnhenn L, Akhras S, Spengler C, Boller K, Pfeiffer KH, Hildt E (2019): Formation of semi-enveloped particles as a unique feature of a hepatitis B virus PreS1 deletion mutant.
Aliment Pharmacol Ther 50: 940-954.
Online-Abstract

Klug B, Schnierle B, Trebesch I (2020): Monoklonale Antikörper zur antiinfektiven Therapie.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1396-1402.
Online-Abstract

Kochhar S, Excler JL, Kim D, Robertson JS, Fast PE, Condit RC, Drew S, Wood D, Gurwith M, Klug B, Whelan M, Khuri-Bulos N, Mallett Moore T, Smith ER, Chen RT, Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) (2020): The Brighton Collaboration standardized template for collection of key information for benefit-risk assessment of inactivated viral vaccines.
Vaccine 38: 6184-6189.
Online-Abstract

Kochhar S, Kim D, Excler JL, Condit RC, Robertson JS, Drew S, Whelan M, Wood D, Fast PE, Gurwith M, Klug B, Khuri-Bulos N, Smith ER, Chen RT, Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) (2020): The Brighton Collaboration standardized template for collection of key information for benefit-risk assessment of protein vaccines.
Vaccine 38: 5734-5739.
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Lin YJ, Anzaghe M, Schülke S (2020): Update on the Pathomechanism, Diagnosis, and Treatment Options for Rheumatoid Arthritis.
Cells 9: E880.
Online-Abstract

Miller L, Klemm J, Schmidt C, KM Hanschmann, Bekeredjian-Ding I, Waibler Z (2019): Individual combinations of danger signals synergistically increase FVIII product immunogenicity.
Haemophilia 25: 996-1002.
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Neubert P, Weichselbaum A, Reitinger C, Schatz V, Schröder A, Ferdinand JR, Simon M, Bär AL, Brochhausen C, Gerlach RG, Tomiuk S, Hammer K, Wagner S, van Zandbergen G, Binger KJ, Müller DN, Kitada K, Clatworthy MR, Kurts C, Titze J, Abdullah Z, Jantsch J (2019): HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting.
Autophagy 15: 1899-1916.
Online-Abstract

Njeru SN, Kraus J, Meena JK, Lechel A, Katz SF, Kumar M, Knippschild U, Azoitei A, Wezel F, Bolenz C, Leithäuser F, Gollowitzer A, Omrani O, Hoischen C, Koeberle A, Kestler HA, Günes C, Rudolph KL (2020): Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor.
Oncogene 39: 1445-1465.
Online-Abstract

Plesker R, Köhler K, von Gerlach S, Boller K, Vogt M, Feder IS (2020): Reactive mesothelial hyperplasia mimicking mesothelioma in an African green monkey (Chlorocebus aethiops).
Primate Biol 7: 5-12.
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Scheer V, Goldammer M, Flindt S, van Zandbergen G, Hinz T (2020): Therapeutische Immunisierungen gegen Tumore und neurodegenerative Erkrankungen.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1373-1379.
Online-Abstract

Turonova B, Sikora M, Schürmann C, Hagen WJH, Welsch S, Blanc FEC, Bülow von S, Gecht M, Bagola K, Hörner C, van Zandbergen G, Mosalaganti S, Schwarz A, Covino R, Mühlebach MD, Hummer G, Krijnse Locker J, Beck M (2020): In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges.
Science 370: 203-208.
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Vieths S, Hildt E, van Zandbergen G (2020): Immuntherapien - Wo stehen wir?.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1319-1321.
Text

Zander H, Müller-Egert S, Zwiewka M, Groß S, van Zandbergen G, Engelbergs J (2020): Checkpointinhibitoren in der Tumortherapie.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1322-1330.
Online-Abstract

Ziegler A, Hinz T, Kalinke U (2019): RNA-Based Adjuvants: Immunoenhancing Effect on Antiviral Vaccines and Regulatory Considerations.
Crit Rev Immunol 39: 1-14.
Online-Abstract

Abteilung Medizinische Biotechnologie

Adney EM, Ochmann MT, Sil S, Truong DM, Mita P, Wang X, Kahler DJ, Fenyö D, Holt LJ, Boeke JD (2019): Comprehensive Scanning Mutagenesis of Human Retrotransposon LINE-1 Identifies Motifs Essential for Function.
Genetics 213: 1401-1414.
Online-Abstract

Agarwal S, Hanauer JDS, Frank AM, Riechert V, Thalheimer FB, Buchholz CJ (2020): In vivo generation of CAR T cells selectively in human CD4+ lymphocytes.
Mol Ther 28: 1783-1794.
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Ali S, Kjeken R, Niederlaender C, Markey G, Saunders TS, Opsata M, Moltu K, Bremnes B, Grønevik E, Muusse M, Håkonsen GD, Skibeli V, Kalland ME, Wang I, Buajordet I, Urbaniak A, Johnston J, Rantell K, Kerwash E, Schuessler-Lenz M, Salmonson T, Bergh J, Gisselbrecht C, Tzogani K, Papadouli I, Pignatti F (2020): The European Medicines Agency Review of Kymriah (Tisagenlecleucel) for the Treatment of Acute Lymphoblastic Leukemia and Diffuse Large B-Cell Lymphoma.
Oncologist 25: e321-e327.
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Amberger M, Ivics Z (2020): Latest Advances for the Sleeping Beauty Transposon System: 23 Years of Insomnia but Prettier than Ever: Refinement and Recent Innovations of the Sleeping Beauty Transposon System Enabling Novel, Nonviral Genetic Engineering Applications.
Bioessays 42: e2000136.
Online-Abstract

Ayyappan Jaguva Vasudevan A, Balakrishnan K, Gertzen CGW, Borveto F, Zhang Z, Sangwiman A, Held U, Küstermann C, Banerjee S, Schumann GG, Häussinger D, Bravo IG, Gohlke H, Münk C (2020): Loop 1 of APOBEC3C regulates its antiviral activity against HIV-1.
J Mol Biol 432: 6200-6227.
Online-Abstract

Baylis SA, Miskey C, Blümel J, Kaiser M, Kapusinszky B, Delwart E (2020): Identification of a Novel Bovine Copiparvovirus in Pooled Fetal Bovine Serum.
Virus Genes 56: 522-526.
Online-Abstract

Bittorf P, Bergmann T, Merlin S, Olgasi C, Pullig O, Sanzenbacher R, Zierau M, Walles H, Follenzi A, Braspenning J (2020): Regulatory-Compliant Validation of a Highly Sensitive qPCR for Biodistribution Assessment of Hemophilia A Patient Cells.
Mol Ther Methods Clin Dev 18: 176-188.
Text

Börger V, Weiss DJ, Anderson JD, Borràs FE, Bussolati B, Carter DRF, Dominici M, Falcón-Pérez JM, Gimona M, Hill AF, Hoffman AM, de Kleijn D, Levine BL, Lim R, Lötvall J, Mitsialis A, Monguió-Tortajada M, Muraca M, Nieuwland R, Nowocin A, O'Driscoll L, Ortiz LA, Phinney DG, Reischl I, Rohde E, Sanzenbacher R, Théry C, Wei ST, Witwer KW, Lim SK, Giebel B (2020): ISEV and ISCT Statement on EVs From MSCs and Other Cells: Considerations for Potential Therapeutic Agents to Suppress COVID-19.
Cytotherapy 22: 482-485.
Online-Abstract

Brown RJP, Tegtmeyer B, Sheldon J, Khera T, Anggakusuma, Todt D, Vieyres G, Weller R, Joecks S, Zhang Y, Sake S, Bankwitz D, Welsch K, Ginkel C, Engelmann M, Gerold G, Steinmann E, Yuan Q, Ott M, Vondran FWR, Krey T, Ströh LJ, Miskey C, Ivics Z, Herder V, Baumgärtner W, Lauber C, Seifert M, Tarr AW, McClure CP, Randall G, Baktash Y, Ploss A, Thi VLD, Michailidis E, Saeed M, Verhoye L, Meuleman P, Goedecke N, Wirth D, Rice CM, Pietschmann T (2020): Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice.
Sci Adv 6: eabd3233.
Online-Abstract

Cathomen T, Schüle S, Schüßler-Lenz M, Abou-El-Enein M (2019): The Human Genome Editing Race: Loosening Regulatory Standards for Commercial Advantage?.
Trends Biotechnol 37: 120-123.
Online-Abstract

Craig-Mueller N, Hammad R, Elling R, Alzubi J, Timm B, Kolter J, Knelangen N, Bednarski C, Gläser B, Ammann S, Ivics Z, Fischer J, Speckmann C, Schwarz K, Lachmann N, Ehl S, Moritz T, Henneke P, Cathomen T (2020): Modeling MyD88 Deficiency In Vitro Provides New Insights in Its Function.
Front Immunol 11: 608802.
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Cullmann K, Blokland KEC, Sebe A, Schenk F, Ivics Z, Heinz N, Modlich U (2019): Sustained and regulated gene expression by Tet-inducible "All-In-One" retroviral vectors containing the HNRPA2B1-CBX3 UCOE.
Biomaterials 192: 486-499.
Online-Abstract

Fintha A, Gasparics Á, Rosivall L, Sebe A (2019): Therapeutic Targeting of Fibrotic Epithelial-Mesenchymal Transition-An Outstanding Challenge.
Front Pharmacol 10: 388.
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Frank AM, Braun AH, Scheib L, Agarwal S, Schneider IC, Fusil F, Perian S, Sahin U, Thalheimer FB, Verhoeyen E, Buchholz CJ (2020): Combining T-cell-specific activation and in vivo gene delivery through CD3-targeted lentiviral vectors.
Blood Adv 4: 5702-5715.
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Frank AM, Buchholz CJ (2019): Surface-Engineered Lentiviral Vectors for Selective Gene Transfer into Subtypes of Lymphocytes.
Mol Ther Methods Clin Dev 12: 19-31.
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Frank AM, Weidner T, Brynza J, Uckert W, Buchholz CJ, Hartmann J (2020): CD8-Specific Designed Ankyrin Repeat Proteins Improve Selective Gene Delivery Into Human and Primate T Lymphocytes.
Hum Gene Ther 31: 679-691.
Online-Abstract

Gao B, Zong W, Miskey C, Ullah N, Diaby M, Chen C, Wang X, Ivics Z, Song C (2020): Intruder (DD38E), a recently evolved sibling family of DD34E/Tc1 transposons in animals.
Mob DNA 11: 32.
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Godehardt AW, Fischer N, Rauch P, Gulich B, Boller K, Church GM, Tönjes RR (2020): Characterization of porcine endogenous retrovirus particles released by the CRISPR/Cas9 inactivated cell line PK15 clone 15.
Xenotransplantation 27: e12563.
Online-Abstract

Godehardt AW, Ramm R, Gulich B, Tönjes RR, Hilfiker A (2020): Decellularized pig pulmonary heart valves-Depletion of nucleic acids measured by proviral PERV pol.
Xenotransplantation 27: e12565.
Online-Abstract

Godehardt AW, Tönjes RR (2020): Xenotransplantation of Decellularized Pig Heart valves-Regulatory Aspects in Europe.
Xenotransplantation 27: e12609.
Online-Abstract

Guan S, Munder A, Hedtfeld S, Braubach P, Glage S, Zhang L, Lienenklaus S, Schultze A, Hasenpusch G, Garrels W, Stanke F, Miskey C, Johler SM, Kumar Y, Tümmler B, Rudolph C, Ivics Z, Rosenecker J (2019): Self-assembled peptide-poloxamine nanoparticles enable in vitro and in vivo genome restoration for cystic fibrosis.
Nat Nanotechnol 14: 287-297.
Online-Abstract

Hartmann J, Thalheimer FB, Höpfner F, Kerzel T, Khodosevich K, García-González D, Monyer H, Diester I, Büning H, Carette JE, Fries P, Buchholz CJ (2019): GluA4-Targeted AAV Vectors Deliver Genes Selectively to Interneurons while Relying on the AAV Receptor for Entry.
Mol Ther Methods Clin Dev 14: 252-260.
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Hawthorne WJ, Cowan PJ, Bühler LH, Yi S, Bottino R, Pierson RN, Ahn C, Azimzadeh A, Cozzi E, Gianello P, Lakey JRT, Luo M, Miyagawa S, Mohiuddin MM, Park CG, Schuurman HJ, Scobie L, Sykes M, Tector J, Tönjes RR, Wolf E, Nuñez JR, Wang W (2019): Third WHO Global Consultation on Regulatory Requirements for Xenotransplantation Clinical Trials, Changsha, Hunan, China December 12-14, 2018: "The 2018 Changsha Communiqué" The 10-Year Anniversary of The International Consultation on Xenotransplantation.
Xenotransplantation 26: e12513.
Online-Abstract

Hernandez M, Recalde S, Garcia-Garcia L, Bezunartea J, Miskey C, Johnen S, Diarra S, Sebe A, Rodriguez-Madoz JR, Pouillot S, Marie C, Izsvák Z, Scherman D, Kropp M, Prosper F, Thumann G, Ivics Z, Garcia-Layana A, Fernandez-Robredo P (2019): Preclinical Evaluation of a Cell-Based Gene Therapy Using the Sleeping Beauty Transposon System in Choroidal Neovascularization.
Mol Ther Methods Clin Dev 15: 403-417.
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Ivics Z, Amberger M, Zahn T, Hildt E (2020): Immuntherapien zur Behandlung der chronischen Hepatitis-B-Virusinfektion - eine Übersicht unter besonderer Berücksichtigung von CAR-T-Zellen.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1357-1364.
Online-Abstract

Ivics Z (2021): Potent CAR-T Cells Engineered With Sleeping Beauty Transposon Vectors Display a Central Memory Phenotype.
Gene Ther 28: 3-5.
Online-Abstract

Jamali A, Kapitza L, Schaser T, Johnston ICD, Buchholz CJ, Hartmann J (2019): Highly Efficient and Selective CAR-Gene Transfer Using CD4- and CD8-Targeted Lentiviral Vectors.
Mol Ther Methods Clin Dev 13: 371-379.
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Kesselring L, Miskey C, Zuliani C, Querques I, Kapitonov V, Laukó A, Fehér A, Palazzo A, Diem T, Lustig J, Sebe A, Wang Y, Dinnyés A, Izsvák Z, Barabas O, Ivics Z (2020): A single amino acid switch converts the Sleeping Beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming.
Nucleic Acids Res 48: 316-331.
Online-Abstract

Kovač A, Miskey C, Menzel M, Grueso E, Gogol-Döring A, Ivics Z (2020): RNA-guided Retargeting of Sleeping Beauty Transposition in Human Cells.
Elife 9: e53868.
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Kurtz A, Elsallab M, Sanzenbacher R, Abou-El-Enein M (2019): Linking Scattered Stem Cell-Based Data to Advance Therapeutic Development.
Trends Mol Med 25: 8-19.
Online-Abstract

Laidou S, Alanis-Lobato G, Pribyl J, Raskó T, Tichy B, Mikulasek K, Tsagiopoulou M, Oppelt J, Kastrinaki G, Lefaki M, Singh M, Zink A, Chondrogianni N, Psomopoulos F, Prigione A, Ivics Z, Pospisoilova S, Skladal P, Izsvák Z, Andrade-Navarro MA, Petrakis S (2020): Nuclear Inclusions of Pathogenic ataxin-1 Induce Oxidative Stress and Perturb the Protein Synthesis Machinery.
Redox Biol 32: 101458.
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Lehmann F, Rau J, Malcolm B, Sander M, von Heymann C, Moormann T, Geyer T, Balzer F, Wernecke KD, Kaufner L (2019): Why does a point of care guided transfusion algorithm not improve blood loss and transfusion practice in patients undergoing high-risk cardiac surgery? A prospective randomized controlled pilot study.
BMC Anesthesiol 19: 24.
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Merker M, Wagner J, Kreyenberg H, Heim C, Moser LM, Wels WS, Bonig H, Ivics Z, Ullrich E, Klingebiel T, Bader P, Rettinger E (2020): ERBB2-CAR-Engineered Cytokine-Induced Killer Cells Exhibit Both CAR-Mediated and Innate Immunity Against High-Risk Rhabdomyosarcoma.
Front Immunol 11: 581468.
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Müller-Berghaus J, Sarac SB, Schüssler-Lenz M (2020): Kombinationstherapien in der Immunonkologie: Differenzierte regulatorische Herangehensweisen.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1388-1395.
Online-Abstract

Palazzo A, Lorusso P, Miskey C, Walisko O, Gerbino A, Marobbio CMT, Ivics Z, Marsano RM1 (2019): Transcriptionally promiscuous "blurry" promoters in Tc1/mariner transposons allow transcription in distantly related genomes.
Mob DNA 10: 13.
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Papadouli I, Mueller-Berghaus J, Beuneu C, Ali S, Hofner B, Petavy F, Tzogani K, Miermont A, Norga K, Kholmanskikh O, Leest T, Schuessler-Lenz M, Salmonson T, Gisselbrecht C, Garcia JL, Pignatti F (2020): EMA Review of Axicabtagene Ciloleucel (Yescarta) for the Treatment of Diffuse Large B-Cell Lymphoma.
Oncologist 25: 894-902.
Online-Abstract

Querques I, Mades A, Zuliani C, Miskey C, Alb M, Grueso E, Machwirth M, Rausch T, Einsele H, Ivics Z, Hudecek M, Barabas O (2019): A highly soluble Sleeping Beauty transposase improves control of gene insertion.
Nat Biotechnol 37: 1502-1512.
Online-Abstract

Reichart B, Längin M, Radan J, Mokelke M, Buttgereit I, Ying J, Fresch AK, Mayr T, Issl L, Buchholz S, Michel S, Ellgass R, Mihalj M, Egerer S, Baehr A, Kessler B, Kemter E, Kurome M, Zakhartchenko V, Steen S, Sjöberg T, Paskevicius A, Krüger L, Fiebig U, Denner J, Godehardt AW, Tönjes RR, Milusev A, Sfriso R, Rieben R, Walz C, Kirchner T, Ayares D, Lampe K, Schönmann U, Hagl C, Wolf E, Klymiuk N, Abicht JM, Brenner P (2020): Pig-to-non-human primate heart transplantation: the final step toward clinical xenotransplantation?.
J Heart Lung Transplant 39: 751-757.
Online-Abstract

Reul J, Muik A, Buchholz CJ (2019): Ligand Coupling to the AAV Capsid for Cell-Specific Gene Transfer.
Methods Mol Biol 1950: 35-50.
Online-Abstract

Sang Y, Gao B, Diaby M, Zong W, Chen C, Shen D, Wang S, Wang Y, Ivics Z, Song C (2019): Incomer, a DD36E family of Tc1/mariner transposons newly discovered in animals.
Mob DNA 10: 45.
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Sanzenbacher R, Frech M (2019): Streitpunkt Eigenfettbehandlung: Wenn Gewebe zur Arznei wird.
Dtsch Arztebl 116: A28-A29, A6.
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Savage AL, Ilera-Lopez A, Iacoangeli A, Bubb VJ, Smith B, Troakes C, Alahmady N, Koks S, Schumann GG, Al-Chalabi A, Quinn JP (2020): Frequency and methylation status of selected retrotransposition competent L1 loci in amyotrophic lateral sclerosis.
Mol Brain 13: 154.
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Savage AL, Schumann GG, Breen G, Bubb VJ, Al-Chalabi A, Quinn JP (2019): Retrotransposons in the development and progression of amyotrophic lateral sclerosis.
J Neurol Neurosurg Psychiatry 90: 284-293.
Online-Abstract

Scheuermann B, Diem T, Ivics Z, Andrade-Navarro MA (2019): Evolution-guided evaluation of the inverted terminal repeats of the synthetic transposon Sleeping Beauty.
Sci Rep 9: 1171.
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Schilling-Leiß D, Frech M, Tönjes RR, Günay-Winter D (2019): Fragen zur Transplantation von humanen Knochenpräparationen und Weichgewebe.
Implantologie 27: 383-385.
Online-Abstract

Schuessler-Lenz M, Enzmann H, Vamvakas S (2020): Regulators' Advice Can Make a Difference: European Medicines Agency Approval of Zynteglo for Beta Thalassemia.
Clin Pharmacol Ther 107: 492-494.
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Schumann GG, Fuchs NV, Tristán-Ramos P, Sebe A, Ivics Z, Heras SR (2019): The impact of transposable element activity on therapeutically relevant human stem cells.
Mob DNA 10: 9.
Text

Sebe A, Anliker B, Rau J, Renner M (2020): Genetisch modifizierte regulatorische T-Zellen: Therapiekonzepte und ihr regulatorischer Rahmen.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1403-1411.
Online-Abstract

Shen D, Gao B, Miskey C, Chen C, Sang Y, Zong W, Wang S, Wang Y, Wang X, Ivics Z, Song C (2020): Multiple Invasions of Visitor, a DD41D Family of Tc1/mariner Transposons, throughout the Evolution of Vertebrates.
Genome Biol Evol 12: 1060-1073.
Online-Abstract

Singh M, Widmann TJ, Vikas Bansal, Cortes JL, Schumann GG, Wunderlich S, Martin U, Garcia-Canadas M, Garcia- Perez JL, Hurst LD, Izsvak Z (2019): The selection arena in early human blastocysts resolves the pluripotent inner cell mass.
bioRxiv Feb 4 [Epub ahead of print].
Online-Abstract

Abteilung Mikrobiologie

Aguirre Dávila L, Koch A, Lasch F (2020): Randomization versus Real-World Evidence.
N Engl J Med 383: e21.
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Ballmer-Weber BK, Lidholm J, Lange L, Pascal M, Lang C, Gernert S, Lozano-Blasco J, Gräni N, Guillod C, Wangorsch A, Hanschmann KM, Pontoppidan B, Tjäder L, Bartra J, Vieths S (2019): Allergen recognition patterns in walnut allergy are age dependent and correlate with the severity of allergic reactions.
J Allergy Clin Immunol Pract 7: 1560-1567.e6.
Online-Abstract

Baylis SA, Hanschmann KM, Matsubayashi K, Sakata H, Roque-Afonso AM, Kaiser M, Corman VM, Kamili S, Aggarwal R, Trehanpati N, Gärtner T, Thomson EC, Davis CA, da Silva Filipe A, Abdelrahman TT, Blümel J, Terao E, HEV collaborative study group (2019): Development of a World Health Organization International Reference Panel for different genotypes of hepatitis E virus for nucleic acid amplification testing.
J Clin Virol 119: 60-67.
Online-Abstract

Behrensdorf-Nicol HA, Bonifas U, Klimek J, Hanschmann KM, Dorner BG, Hohenadl C, Töllner L, Kegel B, Krämer B (2020): Transferability study of the BINACLE (binding and cleavage) assay for in vitro determination of botulinum neurotoxin activity.
Biologicals 67: 81-87.
Online-Abstract

Bekeredjian-Ding I, Pletz MW (2019): Impfung gegen endogene Infektionen mit Antibiotika-resistenten Bakterien.
Trillium Immunologie 3: 178-183.
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Bekeredjian-Ding I, van Molle W, Baay M, Neels P, PEI speakers and session chairs (2020): Human challenge trial workshop: Focus on quality requirements for challenge agents, Langen, Germany, October 22, 2019.
Biologicals 66: 53-61.
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Bolden J, Knutsen C, Levin J, Milne C, Morris T, Mozier N, Spreitzer I, von Wintzingerode F (2020): Currently available recombinant alternatives to horseshoe crab blood lysates: Are they comparable for the detection of environmental bacterial endotoxins? A Review.
PDA J Pharm Sci Technol 74: 602-611.
Online-Abstract

Cerezales M, Xanthopoulou K, Wille J, Krut O, Seifert H, Gallego L, Higgins PG (2020): Mobile Genetic Elements Harboring Antibiotic Resistance Determinants in Acinetobacter baumannii Isolates From Bolivia.
Front Microbiol 11: 919.
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Collignon O, Gartner C, Haidich AB, James Hemmings R, Hofner B, Pétavy F, Posch M, Rantell K, Roes K, Schiel A (2020): Current statistical considerations and regulatory perspectives on the planning of confirmatory basket, umbrella and platform trials.
Clin Pharmacol Ther 107: 1059-1067.
Online-Abstract

Etna MP, Giacomini E, Rizzo F, Severa M, Ricci D, Shaid S, Lambrigts D, Valentini S, Galli Stampino L, Alleri L, Gaggioli A, Von Hunolstein C, Spreitzer I, Coccia EM (2020): Optimization of the monocyte-activation-test for evaluating pyrogenicity of tick-borne encephalitis virus vaccine.
ALTEX 37: 532-544.
Online-Abstract

Fiedler SA, Boller K, Junker AC, Kamp C, Hilger A, Schwarz W, Seitz R, Salge-Bartels U (2020): Evaluation of the in vitro function of platelet concentrates from pooled buffy coats or apheresis.
Transfus Med Hemother 47: 314-324.
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Goeser F, Münch P, Lesker TR, Lutz PL, Krämer B, Kaczmarek DJ, Finnemann C, Nischalke HD, Geffers R, Parcina M, McHardy A, Strassburg C, Hoerauf A, Nattermann J, Bekeredjian-Ding I, Spengler U (2020): Neither Black Nor White: Do Altered Intestinal Microbiota Reflect Chronic Liver Disease Severity?.
Gut 70: 438-440.
Online-Abstract

Götz K, Bekeredjian-Ding I: Immunprophylaxe gegen die Antibiotika-assoziierte Diarrhö.
In: Roeb E, Kempf VAJ (Hrsg.), Leitsymptom Diarrhö: De Gruyter, 2019. S. 277-302, ISBN 978-3-11-053753-6

Gräf C, Hoffmann I, Diefenbach C, König J, Schmidt MF, Schnick-Vollmer K, Huss M, Urschitz MS (2019): Mental health problems and school performance in first graders: results of the prospective cohort study ikidS.
Eur Child Adolesc Psychiatry 28: 1341-1352.
Online-Abstract

Herb M, Gluschko A, Wiegmann K, Farid A, Wolf A, Utermöhlen O, Krut O, Krönke M, Schramm M (2019): Mitochondrial reactive oxygen species enable proinflammatory signaling through disulfide linkage of NEMO.
Sci Signal 12: eaar5926.
Online-Abstract

Jakubovski E, Pisarenko A, Fremer C, Haas M, May M, Schumacher C, Schindler C, Häckl S, Aguirre Davila L, Koch A, Brunnauer A, Cimpianu CL, Lutz B, Bindila L, Müller-Vahl K (2020): The CANNA-TICS Study Protocol: A Randomized Multi-Center Double-Blind Placebo Controlled Trial to Demonstrate the Efficacy and Safety of Nabiximols in the Treatment of Adults With Chronic Tic Disorders.
Front Psychiatry 11: 575826.
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Kress J, Vermeulen M, Chudy M, Reissinger A, Hanschmann KM, Saville A, Nübling CM (2020): Reliability of CE-marked NATs for HIV-1 subtype C detection and quantitation.
J Clin Virol 132: 104649.
Online-Abstract

Lima Leite E, Gautron A, Deplanche M, Nicolas A, Ossemond J, Nguyen MT, do Carmo FLR, Gilot D, Azevedo V, Götz F, Le Loir Y, Otto M, Berkova N (2020): Involvement of caspase-1 in inflammasomes activation and bacterial clearance in S. aureus-infected osteoblast-like MG-63 cells.
Cell Microbiol 22: e13204.
Online-Abstract

Loessner H, Schlattmeier I, Anders-Maurer M, Bekeredjian-Ding I, Rohde C, Wittmann J, Pokalyuk C, Krut O, Kamp C (2020): Kinetic Fingerprinting Links Bacteria-Phage Interactions with Emergent Dynamics: Rapid Depletion of Klebsiella pneumoniae Indicates Phage Synergy.
Antibiotics (Basel) 9: 408.
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Matheis W, Bekeredjian-Ding I (2019): Raman-Spektroskopie: 'Gefakte' Impfstoffe aufspüren.
Dtsch Arztebl 116: A2192-A3.
Text

Miller L, Klemm J, Schmidt C, KM Hanschmann, Bekeredjian-Ding I, Waibler Z (2019): Individual combinations of danger signals synergistically increase FVIII product immunogenicity.
Haemophilia 25: 996-1002.
Text

Nguyen MT, Saising J, Tribelli PM, Nega M, Diene SM, François P, Schrenzel J, Spröer C, Bunk B, Ebner P, Hertlein T, Kumari N, Härtner T, Wistuba D, Voravuthikunchai SP, Mäder U, Ohlsen K, Götz F (2019): Inactivation of farR Causes High Rhodomyrtone Resistance and Increased Pathogenicity in Staphylococcus aureus.
Front Microbiol 10: 1157.
Online-Abstract

Prax M, Bekeredjian-Ding I, Krut O (2019): Microbiological Screening of Platelet Concentrates in Europe.
Transfus Med Hemother 46: 76-86.
Online-Abstract

Prax M, Spindler-Raffel E, McDonald CP, Bearne J, Satake M, Kozakai M, Rojo J, Hanschmann KO, Lambrecht B, Grundmann U, O'Flaherty N, Klimek A, Bekeredjian-Ding I, Gathof BS, Störmer M, Süßner S, Renke C, Lee CK, Knabbe C, Volllmer T, Keil SD, Shipps ME, Wagner SJ, Jentsch U, Mpumlwana X, Cloutier M, Bringmann P, Lu T, Ramirez-Arcos S, Kou Y, Krut O, ISBT Transfusion-Transmitted Infectious Diseases Working Party, Subgroup on Bacteria (2020): Establishment of Transfusion-Relevant Bacteria Reference Strains for Red Blood Cells.
Vox Sang Dec 20 [Epub ahead of print].
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Ramirez-Arcos S, McDonald C, Deol P, Kreuger AL, Patel N, Pidcoke H, Prax M, Seltsam A, Stassinopoulos A, The ISBT Working Party on Transfusion‐Transmitted Infectious Diseases, Subgroup on Bacteria (2019): Bacterial safety of blood components–a congress review of the ISBT transfusion‐transmitted infectious diseases working party, bacterial subgroup.
ISBT Sci Ser 14: 239-247.
Text

Rauch G, Röhmel J, Gerß J, Scherag A, Hofner B (2019): Aktuelle Herausforderungen bei der Bewertung von Ethikanträgen – Aspekte der Digitalisierung und Personalisierung im Gesundheitswesen.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 62: 758-764.
Online-Abstract

Silge A, Matheis W, Becker B, Bocklitz T, Popp J, Bekeredjian-Ding I (2019): Raman-Spektroskopie zur Prüfung von Impfstoffen.
GIT Labor-Fachzeitschrift 63: 46-48.
Text

Singh S, Akhter MS, Dodt J, Volkers P, Reuter A, Reinhart C, Krettler C, Oldenburg J, Biswas A (2019): Identification of Potential Novel Interacting Partners for Coagulation Factor XIII B (FXIII-B) Subunit, a Protein Associated with a Rare Bleeding Disorder.
Int J Mol Sci 20: 2682.
Online-Abstract

Smith A, Hofner B, Lamb JS, Osenkowski J, Allison T, Sadoti G, McWilliams SR, Paton P (2019): Modeling spatiotemporal abundance of mobile wildlife in highly variable environments using boosted GAMLSS hurdle models.
Ecol Evol 9: 2346-2364.
Text

Spreitzer I: Evolution and Characteristics of the Monocyte Activation Test (MAT).
In: Williams K (Hrsg.), Endotoxin Detection and Control in Pharma, Limulus, and Mammalian Systems: Springer International Publishing, 2019. S. 523-535, ISBN 978-3-030-17147-6

Tribelli PM, Luqman A, Nguyen MT, Madlung J, Fan SH, Macek B, Sass P, Bitschar K, Schittek B, Kretschmer D, Götz F (2020): Staphylococcus aureus Lpl protein triggers human host cell invasion via activation of Hsp90 receptor.
Cell Microbiol 22: e13111.
Online-Abstract

Trösemeier JH, Rudorf S, Loessner H, Hofner B, Reuter A, Schulenborg T, Koch I, Bekeredjian-Ding I, Lipowsky R, Kamp C (2019): Optimizing the dynamics of protein expression.
Sci Rep 9: 7511.
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Uebele J, Habenicht K, Ticha O, Bekeredjian-Ding I (2020): Staphylococcus aureus Protein A Induces Human Regulatory T Cells Through Interaction With Antigen-Presenting Cells.
Front Immunol 11: 581713.
Online-Abstract

Volkers P, Hanschmann KM, Chambost H, Collins PW, Demiguel V, Hart DP, Hay CRM, Goudemand J, Ljung R, Palmer BP, Santagostino E, van Hardeveld EM, van den Berg M, Keller-Stanislawski B (2019): Recombinant factor VIII products and inhibitor development in previously untreated patients with severe haemophilia A: Combined analysis of three studies.
Haemophilia 25: 398-407.
Online-Abstract

Weisser K, Göen T, Oduro JD, Wangorsch G, Hanschmann KO, Keller-Stanislawski B (2020): Aluminium from adjuvanted subcutaneous allergen immunotherapeutics in rats is mainly detected in bone.
Allergy 75: 215-217.
Online-Abstract

Weisser K, Göen T, Oduro JD, Wangorsch G, Hanschmann KO, Keller-Stanislawski B (2019): Aluminium toxicokinetics after intramuscular, subcutaneous, and intravenous injection of Al citrate solution in rats.
Arch Toxicol 93: 37-47.
Online-Abstract

Weisser K, Göen T, Oduro JD, Wangorsch G, Hanschmann KO, Keller-Stanislawski B (2019): Aluminium in plasma and tissues after intramuscular injection of adjuvanted human vaccines in rats.
Arch Toxicol 93: 2787-2796.
Online-Abstract

Xanthopoulou K, Carattoli A, Wille J, Biehl LM, Rohde H, Farowski F, Krut O, Villa L, Feudi C, Seifert H, Higgins PG (2020): Antibiotic Resistance and Mobile Genetic Elements in Extensively Drug-Resistant Klebsiella pneumoniae Sequence Type 147 Recovered from Germany.
Antibiotics (Basel) 9: 675.
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Abteilung Sicherheit von Arzneimitteln und Medizinprodukten

Barth I (2019): Kontraindikation von Crysvita (Burosumab).
Bulletin zur Arzneimittelsicherheit 10: 22-23.
Text

Berg P, Heiden M, Müller S, Oberle D, Funk M, Keller-Stanislawski B (2020): SARS-CoV-2-Infektionen und Sicherheit von Blut und Blutkomponenten.
Bulletin zur Arzneimittelsicherheit 11: 17-19.
Text

Blankenbach K, Schwab N, Hofner B, Adams O, Keller-Stanislawski B, Warnke C (2019): Natalizumab-associated progressive multifocal leukoencephalopathy in Germany.
Neurology 92: e2232-e2239.
Online-Abstract

Corman VM, Rabenau HF, Adams O, Oberle D, Funk MB, Keller-Stanislawski B, Timm J, Drosten C, Ciesek S (2020): SARS-CoV-2 asymptomatic and symptomatic patients and risk for transfusion transmission.
Transfusion 60: 1119-1122.
Online-Abstract

Domanovíc D, Ushiro-Lamb, Compernolle V, Brusin S, Funk M, Gallian P, Georgsen J, Janssen M, Jiminez-Marco T, Knutson F, Liumbruno GM, Mali P, Marano G, Maryuningsih Y, Niederhauser C, Politis C, Pupella S, Rautmann G, Saadat K, Sandid I, Sousa AP, Vaglio S, Velati C, Verdun N, Vesga M, Rebulla P (2019): Pathogen reduction of blood components during outbreaks of infectious diseases in the European Union: an expert opinion from the European Centre for Disease Prevention and Control consultation meeting.
Blood Transfus 17: 433-448.
Online-Abstract

Fiedler SA, Boller K, Junker AC, Kamp C, Hilger A, Schwarz W, Seitz R, Salge-Bartels U (2020): Evaluation of the in vitro function of platelet concentrates from pooled buffy coats or apheresis.
Transfus Med Hemother 47: 314-324.
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Fiedler SA, Oberle D, Chudy M, Scheiblauer H, Henseler O, Halbauer J, Heiden M, Funk MB (2019): Effectiveness of blood donor screening by HIV, HCV, HBV‐NAT assays, as well as HBsAg and anti‐HBc immunoassays in Germany (2008–2015).
Vox Sang 114: 443-450.
Online-Abstract

Fiedler SA, Oberle D, Heiden M, Funk MB (2019): Untersuchung zum Nutzen zusätzlicher Testverfahren in Deutschland für die Sicherheit von Blutkomponenten und Blutprodukten.
Bulletin zur Arzneimittelsicherheit 10: 37-40.
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Iannuzzi F, Sirabella R, Canu N, Maier TJ, Annunziato L, Matrone C (2020): Fyn Tyrosine Kinase Elicits Amyloid Precursor Protein Tyr682 Phosphorylation in Neurons from Alzheimer's Disease Patients.
Cells 9: E1807.
Online-Abstract

Keller-Stanislawski B (2019): PML-Risiko bei Behandlung der multiplen Sklerose mit Tysabri bei anti-JCV-Antikörper-positiven Patienten abhängig vom Dosierungsintervall.
Bulletin zur Arzneimittelsicherheit 10: 29-35.
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Keller-Stanislawski B, Oberle D: Nebenwirkungen von Schutzimpfungen.
In: Grandt D, Lappe V, Schubert I (Hrsg.), Arzneimittelreport 2019: Impfungen bei Kindern und Jugendlichen: Barmer, 2019. S. 190-197, ISBN 978-3-946199-22-9
(Schriftenreihe zur Gesundheitsanalyse 16)

Mahler V, Bonertz A, Ruoff C, Hartenstein D, Mentzer D, Kaul S, Vieths S (2019): What we learned from TAO - 10 years of German therapy allergen ordinance.
Allergo J Int 28: 330-337.
Online-Abstract

Mahler V, Mentzer D, Bonertz A, Muraro A, Eigenmann P, Bousquet J, Halken S, Pfaar O, Jutel M, Wahn U, Vieths S, Kaul S (2020): Allergen Immunotherapy (AIT) in children: a vulnerable population with its own rights and legislation - summary of EMA-initiated multi-stakeholder meeting on Allergen Immunotherapy (AIT) for children, held at Paul-Ehrlich-Institut, Langen, Germany, 16.1.2019.
Clin Transl Allergy 10: 28.
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Mangtani P, Evans SJW, Lange B, Oberle D, Smith J, Drechsel-Baeuerle U, Keller-Stanislawski B (2020): Safety profile of rubella vaccine administered to pregnant women: A systematic review of pregnancy related adverse events following immunisation, including congenital rubella syndrome and congenital rubella infection in the foetus or infant.
Vaccine 38: 963-978.
Online-Abstract

Mentzer D, Keller-Stanislawski B (2020): Daten zur Pharmakovigilanz von Impfstoffen aus dem Jahr 2018.
Bulletin zur Arzneimittelsicherheit 11: 15-22.
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Mentzer D, Oberle D, Keller-Stanislawski B (2019): Daten zur Pharmakovigilanz von Impfstoffen aus dem Jahr 2017.
Bulletin zur Arzneimittelsicherheit 10: 19-27.
Text

Morgenroth A, Jakel V, Hanke-Robinson H, Müller T, Freuling C, Cussler K, Duchow K, Krämer B, Bastian M (2020): A Novel Electrophoretic Immunoblot as Antigen Desorption and Quantification Method for Alum-Adjuvanted Veterinary Rabies Vaccines.
Vaccine 38: 4281-4287.
Online-Abstract

Nguyen MTH, Ott JJ, Caputo M, Keller-Stanislawski B, Klett-Tammen CJ, Linnig S, Mentzer D, Krause G (2020): User preferences for a mobile application to report adverse events following vaccination.
Pharmazie 75: 27-31.
Online-Abstract

Oberle D, Drechsel-Bäuerle U, Keller-Stanislawski B (2020): Sicherheitsprofil von Rötelnimpfstoffen bei (versehentlicher) Impfung in der Schwangerschaft.
Bulletin zur Arzneimittelsicherheit 11: 23-31.
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Oberle D, Hoffelner M, Pavel J, Mentzer D, Barth I, Drechsel-Bäuerle U, Keller-Stanislawski B (2020): Risikofaktoren für Invagination bei Kindern unter einem Jahr mit Schwerpunkt Rotavirusimpfstoffe: retrospektive multizentrische gematchte Fall-Kontrolle-Studie.
Bulletin zur Arzneimittelsicherheit 11: 10-19.
Text

Oberle D, Hoffelner M, Pavel J, Mentzer D, Barth I, Drechsel-Bäuerle U, Keller-Stanislawski (2020): Retrospective Multicenter Matched Case-Control Study on the Risk Factors for Intussusception in Infants Less Than 1 Year of Age With a Special Focus on Rotavirus Vaccines - The German Intussusception Study.
Hum Vaccin Immunother 16: 2481-2494.
Online-Abstract

Oberle D, Mentzer D, Keller-Stanislawski B (2019): Umgang mit Verdachtsfällen von Impfnebenwirkungen und -komplikationen.
Trillium Immunologie 3: 173-177.
Text

Oberle D, Mentzer D, Rocha F, Streit R, Weißer K, Keller-Stanislawski B (2019): Impfkomplikationen und der Umgang mit Verdachtsfällen.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 62: 450-461.
Online-Abstract

Oberle D, Mentzer D, Rocha F, Streit R, Weisser K, Keller-Stanislawski B (2019): Komplikationen nach Schutzimpfungen bei Kindern und Erwachsenen mit Hinweis auf einen kausalen Zusammenhang.
Bulletin zur Arzneimittelsicherheit 10: 15-21.
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Oberle D, Mentzer D, Weber G (2020): Befragung zur Verträglichkeit der Impfstoffe gegen das neue Coronavirus (SARS-CoV-2) mittels Smartphone-App SafeVac 2.0.
Bulletin zur Arzneimittelsicherheit 11: 27-31.
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Piesche M, Roos J, Kühn B, Fettel J, Hellmuth N, Brat C, Maucher IV, Awad O, Matrone C, Comerma Steffensen SG, Manolikakes G, Heinicke U, Zacharowski KD, Steinhilber D, Maier TJ (2020): The Emerging Therapeutic Potential of Nitro Fatty Acids and Other Michael Acceptor-Containing Drugs for the Treatment of Inflammation and Cancer.
Front Pharmacol 11: 1297.
Text

Sanzenbacher R, Frech M (2019): Streitpunkt Eigenfettbehandlung: Wenn Gewebe zur Arznei wird.
Dtsch Arztebl 116: A28-A29, A6.
Text

Sauter-Louis CM, Staubach C, Reichmann F, Stoll A, Rademacher G, Cussler K, Bastian M, Pfitzner-Friedrich A (2020): Spatial Distribution and Incidence of Bovine Neonatal Pancytopenia in Bavaria, Germany.
BMC Vet Res 16: 155.
Online-Abstract

Scheiblauer H, Heiden M, Funk MB, Oberle D, Kreß J, Jork C, Chudy M (2020): Detection of hepatitis B virus infection in German blood donors 2008-2015.
Vox Sang 115: 152-161.
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Seltzer JH, Farrell A, Goldenberg N, Hornik C, Keene D, Krucoff MW, Lipardi C, Massicotte P, Mentzer D, Monagle P, Thornburg C, Revkin JH, Walker S, Gajjar D (2020): Defining the path ahead for NOAC use in the pediatric population: A Cardiac Safety Research Consortium Think Tank.
Am Heart J 224: 138-147.
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Viviani L, Halder M, Gruber M, Bruckner L, Cussler K, Sanyal G, Srinivas G, Goel S, Kaashoek M, Litthauer D, Lopes da Silva AL, Sakanyan E, Aprea P, Jin H, Vandeputte J, Seidle T, Yakunin D (2020): Global harmonization of vaccine testing requirements: Making elimination of the ATT and TABST a concrete global achievement.
Biologicals 63: 101-105.
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Volkers P, Hanschmann KM, Chambost H, Collins PW, Demiguel V, Hart DP, Hay CRM, Goudemand J, Ljung R, Palmer BP, Santagostino E, van Hardeveld EM, van den Berg M, Keller-Stanislawski B (2019): Recombinant factor VIII products and inhibitor development in previously untreated patients with severe haemophilia A: Combined analysis of three studies.
Haemophilia 25: 398-407.
Online-Abstract

Weisser K, Göen T, Oduro JD, Wangorsch G, Hanschmann KO, Keller-Stanislawski B (2020): Aluminium from adjuvanted subcutaneous allergen immunotherapeutics in rats is mainly detected in bone.
Allergy 75: 215-217.
Online-Abstract

Weisser K, Göen T, Oduro JD, Wangorsch G, Hanschmann KO, Keller-Stanislawski B (2019): Aluminium toxicokinetics after intramuscular, subcutaneous, and intravenous injection of Al citrate solution in rats.
Arch Toxicol 93: 37-47.
Online-Abstract

Weisser K, Göen T, Oduro JD, Wangorsch G, Hanschmann KO, Keller-Stanislawski B (2019): Aluminium in plasma and tissues after intramuscular injection of adjuvanted human vaccines in rats.
Arch Toxicol 93: 2787-2796.
Online-Abstract

Weisser K, Keller-Stanislawski B (2019): Daten zur Aluminiumkinetik nach Verabreichung von aluminiumbasierten Adjuvanzien in Ratten.
Bulletin zur Arzneimittelsicherheit 10: 31-34.
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Wenzel A, Schwedinger E, Kulezic B, Cußler K (2019): Pharmakovigilanzreport Tierimpfstoffe: Analyse der Nebenwirkungsmeldungen aus den Jahren 2016 und 2017.
DTBl 67: 1270-1276.
Volltext

Wenzel A, Thomas J (2020): Pharmakovigilanzreport Tierimpfstoffe: Analyse der Nebenwirkungsmeldungen aus den Jahren 2018 und 2019.
DTBl 68: 1496-1500.
Volltext

Abteilung Veterinärmedizin

Anderson DE, Pfeffermann K, Kim SY, Sawatsky B, Pearson J, Kovtun M, Corcoran DL, Krebs Y, Sigmundsson K, Jamison SF, Yeo ZZJ, Rennick LJ, Wang LF, Talbot PJ, Duprex WP, Garcia-Blanco MA, von Messling V (2019): Comparative loss of function screens reveal ABCE1 as an essential cellular 1 host factor for efficient translation of Paramyxoviridae and Pneumoviridae.
mBio 10: e00826-19.
Text

Ayasoufi K, Pfaller CK (2020): Seek and hide: the manipulating interplay of measles virus with the innate immune system.
Curr Opin Virol 41: 18-30.
Online-Abstract

Ayasoufi K, Pfaller CK, Evgin L, Khadka RH, Tritz ZP, Goddery EN, Fain CE, Yokanovich LT, Himes BT, Jin F, Zheng J, Schuelke MR, Hansen MJ, Tung W, Parney IF, Pease LR, Vile RG, Johnson AJ (2020): Brain cancer induces systemic immunosuppression through release of non-steroid soluble mediators.
Brain 143: 3629-3652.
Online-Abstract

Behrensdorf-Nicol HA, Bonifas U, Klimek J, Hanschmann KM, Dorner BG, Hohenadl C, Töllner L, Kegel B, Krämer B (2020): Transferability study of the BINACLE (binding and cleavage) assay for in vitro determination of botulinum neurotoxin activity.
Biologicals 67: 81-87.
Online-Abstract

Behrensdorf-Nicol HA, Krämer B (2019): Is the test for irreversibility of tetanus toxoids still relevant?.
Vaccine 37: 1721-1724.
Online-Abstract

Braun E, Hotter D, Koepke L, Zech F, Groß R, Sparrer KMJ, Müller JA, Pfaller CK, Heusinger E, Wombacher R, Sutter K, Dittmer U, Winkler M, Simmons G, Jakobsen MR, Conzelmann KK, Pöhlmann S, Münch J, Fackler OT, Kirchhoff F, Sauter D (2019): Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins.
Cell Rep 27: 2092-2104.e10.
Online-Abstract

Brown RJP, Tegtmeyer B, Sheldon J, Khera T, Anggakusuma, Todt D, Vieyres G, Weller R, Joecks S, Zhang Y, Sake S, Bankwitz D, Welsch K, Ginkel C, Engelmann M, Gerold G, Steinmann E, Yuan Q, Ott M, Vondran FWR, Krey T, Ströh LJ, Miskey C, Ivics Z, Herder V, Baumgärtner W, Lauber C, Seifert M, Tarr AW, McClure CP, Randall G, Baktash Y, Ploss A, Thi VLD, Michailidis E, Saeed M, Verhoye L, Meuleman P, Goedecke N, Wirth D, Rice CM, Pietschmann T (2020): Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice.
Sci Adv 6: eabd3233.
Online-Abstract

Carpentier A, Sheldon J, Vondran FWR, Brown RJ, Pietschmann T (2020): Efficient Acute and Chronic Infection of Stem Cell-Derived Hepatocytes by Hepatitis C Virus.
Gut 69: 1659-1666.
Text

Cattaneo R, Donohue RC, Generous AR, Navaratnarajah CK, Pfaller CK (2019): Stronger together: Multi-genome transmission of measles virus.
Virus Res 265: 74-79.
Online-Abstract

Cullmann K, Blokland KEC, Sebe A, Schenk F, Ivics Z, Heinz N, Modlich U (2019): Sustained and regulated gene expression by Tet-inducible "All-In-One" retroviral vectors containing the HNRPA2B1-CBX3 UCOE.
Biomaterials 192: 486-499.
Online-Abstract

Demminger DE, Walz L, Dietert K, Hoffmann H, Planz O, Gruber AD, von Messling V, Wolff T (2020): Adeno-associated Virus-Vectored Influenza Vaccine Elicits Neutralizing and Fcγ Receptor-Activating Antibodies.
EMBO Mol Med 12: e10938.
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Duecker R, Baer PC, Buecker A, Huenecke S, Pfeffermann LM, Modlich U, Bakhtiar S, Bader P, Zielen S, Schubert R (2020): Hematopoietic Stem Cell Transplantation Restores Naïve T-Cell Populations in Atm-Deficient Mice and in Preemptively Treated Patients With Ataxia-Telangiectasia.
Front Immunol 10: 2785.
Text

Enkirch T, Sauber S, Anderson DE, Gan ES, Kenanov D, Maurer-Stroh S, von Messling V (2019): Identification and In Vivo Efficacy Assessment of Approved Orally Bioavailable Human Host Protein-Targeting Drugs with Broad Anti-Influenza A Activity.
Front Immunol 10: 1097.
Text

Farrukee R, Tai CM, Oh DY, Anderson DE, Gunalan V, Hibberd M, Lau GY, Barr IG, von Messling V, Maurer-Stroh S, Hurt AC (2020): Utilising animal models to evaluate oseltamivir efficacy against influenza A and B viruses with reduced in vitro susceptibility.
PLoS Pathog 16: e1008592.
Text

Hanauer JRH, Koch V, Lauer UM, Mühlebach MD (2019): High-Affinity DARPin Allows Targeting of MeV to Glioblastoma Multiforme in Combination with Protease Targeting without Loss of Potency.
Mol Ther Oncolytics 15: 186-200.
Online-Abstract

Hörner C, Schürmann C, Auste A, Ebenig A, Muraleedharan S, Dinnon KH, Scholz T, Herrmann M, Schnierle B, Baric RS, Mühlebach MD (2020): A Highly Immunogenic Measles Virus-based Th1-biased COVID-19 Vaccine.
Proc Natl Acad Sci USA 117: 32657-32666.
Text

Kerber R, Lorenz E, Duraffour S, Sissoko D, Rudolf M, Jaeger A, Cisse SD, Camara AM, Miranda O, Castro CM, Akoi Bore J, Koundouno FM, Repits J, Afrough B, Becker-Ziaja B, Hinzmann J, Mertens M, Vitoriano I, Logue CL, Böttcher JP, Pallasch E, Sachse A, Bah A, Cabenza-Cabrezio M, Nitzsche K, Kuisma E, Michel J, Holm T, Zekeng EG, Cowley LA, Garcia-Dorival I, Hetzelt N, Baum JHJ, Portmann J, Carter L, Yenamaberhan RL, Camino A, Enkirch T, Singethan K, Meisel S, Mazzarelli A, Kosgei A, Kafetzopoulou L, Rickett NY, Patrono LV, Ghebreghiorghis L, Arnold U, Colin G, Juchet S, Marchal CL, Kolie JS, Beavogui AH, Wurr S, Bockholt S, Krumkamp R, May J, Stoecker K, Fleischmann E, Ippolito G, Carroll MW, Koivogui L, Magassouba N, Keita S, Gurry C, Drury P, Diallo B, Formenty P, Wölfel R, Di Caro A, Gabriel M, Anglaret X, Malvy D, Günther S (2019): Laboratory Findings, Compassionate Use of Favipiravir, and Outcome in Patients With Ebola Virus Disease, Guinea, 2015-A Retrospective Observational Study.
J Infect Dis 220: 195-202.
Text

Kinast V, Leber SL, Brown RJP, Vieyres G, Behrendt P, Eßbach C, Strnad P, Vondran FWR, Cornberg M, Wex C, Pietschmann T, Haybaeck J, Todt D, Steinmann E (2019): Identification of Keratin 23 as a Hepatitis C Virus-Induced Host Factor in the Human Liver.
Cells 8: 610.
Text

Kinast V, Plociennikowska A, Anggakusuma, Bracht T, Todt D, Brown RJP, Boldanova T, Zhang Y, Brueggemann Y, Friesland M, Engelmann M, Vieyres G, Broering R, Vondran FWR, Heim MH, Sitek B, Bartenschlager R, Pietschmann T, Steinmann E (2020): C19orf66 is an interferon-induced inhibitor of HCV replication that restricts formation of the viral replication organelle.
J Hepatol 73: 549-558.
Online-Abstract

Kleinert RDV, Montoya-Diaz E, Khera T, Welsch K, Tegtmeyer B, Hoehl S, Ciesek S, Brown RJP (2019): Yellow Fever: Integrating Current Knowledge with Technological Innovations to Identify Strategies for Controlling a Re-Emerging Virus.
Viruses 11: 960.
Text

Kohlscheen S, Schenk F, Rommel M, Cullmann K, Modlich U (2019): Endothelial protein C receptor supports hematopoietic stem cell engraftment and expansion in Mpl-deficient mice.
Blood 133: 1465-1478.
Online-Abstract

López-Camacho C, Kim YC, Blight J, Lazaro Moreli M, Montoya-Diaz E, Huiskonen JT, Kümmerer BM, Reyes-Sandoval A (2019): Assessment of Immunogenicity and Neutralisation Efficacy of Viral-Vectored Vaccines Against Chikungunya Virus.
Viruses 11: 322.
Text

Morgenroth A, Jakel V, Hanke-Robinson H, Müller T, Freuling C, Cussler K, Duchow K, Krämer B, Bastian M (2020): A Novel Electrophoretic Immunoblot as Antigen Desorption and Quantification Method for Alum-Adjuvanted Veterinary Rabies Vaccines.
Vaccine 38: 4281-4287.
Online-Abstract

Mühlebach MD, Cattaneo R: Development of Entry-Targeted Oncolytic Measles Viruses.
In: Engeland C (Hrsg.), Oncolytic Viruses. Methods in Molecular Biology (Vol. 2058). New York, NY: Humana, 2019. S. 51-75, ISBN 978-1-4939-9794-7

Mühlebach MD (2020): Measles virus in cancer therapy.
Curr Opin Virol 41: 85-97.
Online-Abstract

Müller S, Bexte T, Gebel V, Kalensee F, Stolzenberg E, Hartmann J, Koehl U, Schambach A, Wels WS, Modlich U, Ullrich E (2020): High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia.
Front Immunol 10: 3123.
Online-Abstract

Müller H, Fehling SK, Dorna J, Urbanowicz RA, Oestereich L, Krebs Y, Kolesnikova L, Schauflinger M, Krähling V, Magassouba N, Fichet-Calvet E, Ball JK, Kaufmann A, Bauer S, Becker S, von Messling V, Strecker T (2020): Adjuvant formulated virus-like particles expressing native-like forms of the Lassa virus envelope surface glycoprotein are immunogenic and induce antibodies with broadly neutralizing activity.
NPJ Vaccines 5: 71.
Online-Abstract

Nürnberger C, Bodmer BS, Fiedler AH, Gabriel G, Mühlebach MD (2019): A measles virus-based vaccine candidate mediates protection against Zika virus in an 1 allogenic mouse pregnancy model.
J Virol 93: e01485-18.
Online-Abstract

Parra-Rojas C, Messling V, Hernandez-Vargas EA (2019): Adjuvanted influenza vaccine dynamics.
Sci Rep 9: 73.
Text

Petrova VN, Sawatsky B, Han AX, Laksono BM, Walz L, Parker E, Pieper K, Anderson CA, de Vries RD, Lanzavecchia A, Kellam P, von Messling V, de Swart RL, Russel CA (2019): Incomplete genetic reconstitution of B cell pools contributes to prolonged immune suppression after measles.
Sci Immunol 4: eaay6125.
Text

Pfaller CK, Bloyet LM, Donohue RC, Huff AL, Bartemes WP, Yousaf I, Urzua E, Clavière M, Zachary M, de Masson d'Autume V, Carson S, Schieferecke AJ, Meyer AJ, Gerlier D, Cattaneo R (2020): The C Protein Is Recruited to Measles Virus Ribonucleocapsids by the Phosphoprotein.
J Virol 94: e01733-19.
Online-Abstract

Plesker R, Berger J (2020): Unintended importation of tropical jumping spiders (Salticidae) into a laboratory monkey colony via banana supply.
Primate Biol 7: 13-17.
Text

Plesker R, Köhler K, von Gerlach S, Boller K, Vogt M, Feder IS (2020): Reactive mesothelial hyperplasia mimicking mesothelioma in an African green monkey (Chlorocebus aethiops).
Primate Biol 7: 5-12.
Text

Rajaraman S, Canjuga D, Ghosh M, Codrea MC, Sieger R, Wedekink F, Tatagiba M, Koch M, Lauer UM, Nahnsen S, Rammensee HG, Mühlebach MD, Stevanovic S, Tabatabai G (2019): Measles Virus-Based Treatments Trigger a Pro-inflammatory Cascade and a Distinctive Immunopeptidome in Glioblastoma.
Mol Ther Oncolytics 12: 147-161.
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Ravindran P, Herrmann M, Cordellier M (2019): Contrasting patterns of divergence at the regulatory and sequence level in European Daphnia galeata natural populations.
Ecol Evol 9: 2487-2504.
Online-Abstract

Rommel MGE, Hoerster K, Milde C, Schenk F, Roser L, Kohlscheen S, Heinz N, Modlich U (2020): Signaling Properties of Murine MPL and MPL Mutants After Stimulation With Thrombopoietin and Romiplostim.
Exp Hermatol 85: 33-46.e6.
Online-Abstract

Rommel MGE, Milde C, Eberle R, Schulze H, Modlich U (2020): Endothelial-platelet interactions in influenza-induced pneumonia: A potential therapeutic target.
Anat Histol Embryol 49: 606-619.
Online-Abstract

Roth H, Schneider L, Eberle R, Lausen J, Modlich U, Blümel J, Baylis SA (2020): Zika Virus Infection Studies With CD34 + Hematopoietic and Megakaryocyte-Erythroid Progenitors, Red Blood Cells and Platelets.
Transfusion 60: 561-574.
Online-Abstract

Schack S, Bodenbender A, Leyhausen M, Altermann F, Eder K, von Messling V, Gyra H (2019): Vergleich von zwei intrakutanen Methoden zur Verabreichung von Rindertuberkulin im Rahmen der allergischen Untersuchung auf bovine Tuberkulose.
Der praktische Tierarzt 100: 578-587.
Online-Abstract

Shin DL, Yang W, Peng JY, Sawatsky B, von Messling V, Herrler G, Wu NH (2020): Avian Influenza A Virus Infects Swine Airway Epithelial Cells Without Prior Adaptation.
Viruses 12: 589.
Online-Abstract

Siering O, Sawatsky B, Pfaller CK (2021): C Protein is Essential for Canine Distemper Virus Virulence and Pathogenicity in Ferrets.
J Virol 95: e01840-20.
Online-Abstract

Singh BK, Pfaller CK, Cattaneo R, Sinn PL (2019): Measles Virus Ribonucleoprotein Complexes Rapidly Spread across Well-Differentiated Primary Human Airway Epithelial Cells along F-Actin Rings.
mBio 10: e02434-19.
Online-Abstract

Tan CW, Wittwer K, Lim XF, Uehara A, Mani S, Wang LF, Anderson DE (2019): Serological evidence and experimental infection of cynomolgus macaques with pteropine orthoreovirus reveal monkeys as potential hosts for transmission to humans.
Emerg Microbes Infect 8: 787-795.
Online-Abstract

Toots M, Yoon JJ, Cox RM, Hart M, Sticher ZM, Makhsous N, Plesker R, Barrena AH, Reddy PG, Mitchell DG, Shean RC, Bluemling GR, Kolykhalov AA, Greninger AL, Natchus MG, Painter GR, Plemper RK (2019): Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia.
Sci Transl Med 11: eaax5866.
Online-Abstract

Turonova B, Sikora M, Schürmann C, Hagen WJH, Welsch S, Blanc FEC, Bülow von S, Gecht M, Bagola K, Hörner C, van Zandbergen G, Mosalaganti S, Schwarz A, Covino R, Mühlebach MD, Hummer G, Krijnse Locker J, Beck M (2020): In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges.
Science 370: 203-208.
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Abteilung Virologie

Adlhoch C, Baylis S (2020): Letter to the Editor: The Emergence of Zoonotic Rat Hepatitis E Virus Infection.
Hepatology 72: 1155.
Online-Abstract

Adlhoch C, Mandákova Z, Ethelberg S, Epstein J, Rimhanen-Finne R, Figoni J, Baylis SA, Faber M, Mellou K, Murphy N, O'Gorman J, Tosti ME, Ciccaglione AR, Hofhuis A, Zaaijer H, Lange H, de Rousa R, Avellón A, Sundqvist L, Said B, Ijaz S (2019): Standardising surveillance of hepatitis E virus infection in the EU/EEA: A review of national practices and suggestions for the way forward.
J Clin Virol 120: 63-67.
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Akhras S, Herrlein ML, Elgner F, Holzhauser T, Hildt E (2019): ZIKV Envelope Domain-Specific Antibodies: Production, Purification and Characterization.
Viruses 11: 748.
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Basic M, Elgner F, Bender D, Sabino C, Herrlein ML, Roth H, Glitscher M, Fath A, Kerl T, Schmalz HG, Hildt E (2019): A synthetic derivative of houttuynoid B prevents cell entry of Zika virus.
Antiviral Res 172: 104644.
Online-Abstract

Baylis SA, Hanschmann KM, Matsubayashi K, Sakata H, Roque-Afonso AM, Kaiser M, Corman VM, Kamili S, Aggarwal R, Trehanpati N, Gärtner T, Thomson EC, Davis CA, da Silva Filipe A, Abdelrahman TT, Blümel J, Terao E, HEV collaborative study group (2019): Development of a World Health Organization International Reference Panel for different genotypes of hepatitis E virus for nucleic acid amplification testing.
J Clin Virol 119: 60-67.
Online-Abstract

Baylis SA, Miskey C, Blümel J, Kaiser M, Kapusinszky B, Delwart E (2020): Identification of a Novel Bovine Copiparvovirus in Pooled Fetal Bovine Serum.
Virus Genes 56: 522-526.
Online-Abstract

Baylis SA, Wallace P, McCulloch E, Niesters HGM, Nübling CM (2019): Standardization of nucleic acid amplification tests: the approach of the World Health Organization.
J Clin Microbiol 57: e01056-18.
Online-Abstract

Bender D, Hildt E (2019): Effect of Hepatitis Viruses on the Nrf2/Keap1-Signaling Pathway and Its Impact on Viral Replication and Pathogenesis.
Int J Mol Sci 20: 4659.
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Blümel J, Schwantes A, Baylis SA, Stühler A (2020): Strategies toward virus and prion safe human platelet lysates.
Transfusion 60: 219-220.
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Chudy M: 11. Development and evaluation of the World health Organization International Standard for the detection of hepatitis D virus RNA.
In: Rizzetto M, Smedile A (Hrsg.), Hepatitis D - Virology, management and methodology. Rome: Il Pensiero Scientifico Editore, 2019. S. 201-221, ISBN 978-88-490-0646-9

Denner J, Pischke S, Steinmann E, Blümel J, Glebe D (2019): Why all blood donations should be tested for hepatitis E virus (HEV).
BMC Infect Dis 19: 541.
Online-Abstract

Fiedler SA, Oberle D, Chudy M, Scheiblauer H, Henseler O, Halbauer J, Heiden M, Funk MB (2019): Effectiveness of blood donor screening by HIV, HCV, HBV‐NAT assays, as well as HBsAg and anti‐HBc immunoassays in Germany (2008–2015).
Vox Sang 114: 443-450.
Online-Abstract

Golsaz-Shirazi F, Asadi-Asadabad S, Sarvnaz H, Mehdi Amiri M, Hojjat-Farsangi M, Chudy M, Jeddi-Tehrani-M, Shokri F (2020): Immunoreactivity pattern of monoclonal antibodies against Hepatitis B vaccine with global Hepatitis B virus genotypes.
Clin Chim Acta 510: 203-210.
Online-Abstract

Grabski E, Hildt E, Wagner R (2020): Zulassungsverfahren für Humanimpfstoffe in Deutschland und Europa und das Präqualifizierungsprogramm der WHO.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 4-15.
Online-Abstract

Haberger V, Elgner F, Roos J, Bender D, Hildt E (2020): Regulation of the Transferrin Receptor Recycling in Hepatitis C Virus-Replicating Cells.
Front Cell Dev Biol 8: 44.
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Henss L, Scholz T, von Rhein C, Wieters I, Borgans F, Eberhardt FJ, Zacharowski K, Ciesek S, Rohde G, Vehreschild M, Stephan C, Wolf T, Hofmann-Winkler H, Scheiblauer H, Schnierle BS (2020): Analysis of humoral immune responses in SARS-CoV-2 infected patients.
J Infect Dis 223: 56-61.
Online-Abstract

Henss L, Yue C, Kandler J, Faddy HM, Simmons G, Panning M, Lewis-Ximenez LL, Baylis SA, Schnierle BS (2019): Establishment of an Alphavirus-Specific Neutralization Assay to Distinguish Infections with Different Members of the Semliki Forest complex.
Viruses 11: 82.
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Henss L, Yue C, von Rhein C, Tschismarov R, Lewis-Ximenez LL, Dölle A, Baylis SA, Schnierle BS (2020): Analysis of humoral immune responses in chikungunya virus (CHIKV) infected patients and individuals vaccinated with a candidate CHIKV vaccine.
J Infect 221: 1713-1723.
Online-Abstract

Hildt E, Ludwig MS, Kuhn J (2019): Impfen neu denken: Ansatzpunkte und Perspektiven einer modernen Impfstrategie.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 62: 383-385.
Online-Abstract

Hörner C, Schürmann C, Auste A, Ebenig A, Muraleedharan S, Dinnon KH, Scholz T, Herrmann M, Schnierle B, Baric RS, Mühlebach MD (2020): A Highly Immunogenic Measles Virus-based Th1-biased COVID-19 Vaccine.
Proc Natl Acad Sci USA 117: 32657-32666.
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Hoffmann J, Chudy M (2019): Hepatitis-E-Virus: Anstehende Konsequenzen für die Transfusionsmedizin.
Hämotherapie 32: 4-8.
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Ivics Z, Amberger M, Zahn T, Hildt E (2020): Immuntherapien zur Behandlung der chronischen Hepatitis-B-Virusinfektion - eine Übersicht unter besonderer Berücksichtigung von CAR-T-Zellen.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1357-1364.
Online-Abstract

Jiang B, Hildt E (2020): Intracellular Trafficking of HBV Particles.
Cells 9: E2023.
Online-Abstract

Jiang B, Peiffer KH, Hildt E (2019): Editorial: HBV-the naked truth? Authors' reply.
Aliment Pharmacol Ther 50: 964-965.
Online-Abstract

Jiang B, Wen X, Wu Q, Bender D, Carra G, Basic M, Kubesch A, Peiffer KH, Boller K, Hildt E (2020): The N-Terminus Makes the Difference: Impact of Genotype-Specific Disparities in the N-Terminal Part of The Hepatitis B Virus Large Surface Protein on Morphogenesis of Viral and Subviral Particles.
Cells 9: E1898.
Online-Abstract

Jiang B, Wu Q, Kuhnhenn L, Akhras S, Spengler C, Boller K, Pfeiffer KH, Hildt E (2019): Formation of semi-enveloped particles as a unique feature of a hepatitis B virus PreS1 deletion mutant.
Aliment Pharmacol Ther 50: 940-954.
Online-Abstract

Juhl D, Chudy M, Görg S, Hennig H (2020): Prevalence of antibodies against Hepatitis D virus (HDV) in blood donors in Northern Germany.
Transfus Apher Sci 59: 102721.
Online-Abstract

Kapsch AM, Farcet MR, Wieser A, Ahmad MQ, Miyabayashi T, Baylis SA, Blümel J, Kreil TR (2020): Antibody-enhanced hepatitis E virus nanofiltration during the manufacture of human immunoglobulin.
Transfusion 60: 2500-2507.
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Khan AS, Blümel J, Deforce D, Gruber MF, Jungbäck C, Knezevic I, Mallet L, Mackay D, Matthijnssens J, O'Leary M, Theuns S, Victoria J, Neels P (2020): Report of the second international conference on next generation sequencing for adventitious virus detection in biologics for humans and animals.
Biologicals 67: 94-111.
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Kishta S, Tabll A, Omanovic Kolaric T, Smolic R, Smolic M (2020): Risk Factors Contributing to the Occurrence and Recurrence of Hepatocellular Carcinoma in Hepatitis C Virus Patients Treated with Direct-Acting Antivirals.
Biomedicines 8: 175.
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Klug B, Schnierle B, Trebesch I (2020): Monoklonale Antikörper zur antiinfektiven Therapie.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1396-1402.
Online-Abstract

Kress J, Vermeulen M, Chudy M, Reissinger A, Hanschmann KM, Saville A, Nübling CM (2020): Reliability of CE-marked NATs for HIV-1 subtype C detection and quantitation.
J Clin Virol 132: 104649.
Online-Abstract

Maddaluno L, Urwyler C, Rauschendorfer T, Meyer M, Stefanova D, Spörri R, Wietecha M, Ferrarese L, Stoycheva D, Bender D, Li N, Strittmatter G, Nasirujjaman K, Beer HD, Staeheli P, Hildt E, Oxenius A, Werner S (2020): Antagonism of interferon signaling by fibroblast growth factors promotes viral replication.
EMBO Mol Med 12: e11793.
Online-Abstract

Mattiuzzo G, Knezevic I, Hassall M, Ashall J, Myhill S, Faulkner V, Hockley J, Rigsby P, Wilkinson DE, Page M, collaborative study participants, Donolato M, Baylis S, Yue C, Elgner F, Yoon IK, Yang JS, Song M, Gonzalez-Escobar G, Brindle R, Tedder R, Dicks S, Ushiro-Lumb I, Williams-McDonald S, Kumar S, Peden K, Golding H, Khurana S, Bonaparte M, Durbin A, Dean H, Sonnberg S, Hogrefe W, Crowe J, Voss T, Collins M, Pierson T, Burgomaster K, Dowd K, Sigismondi L, Gunasekera D, Wassenberg J, Eckels K, De La Barrera R (2019): Harmonization of Zika neutralization assays by using the WHO International Standard for anti-Zika virus antibody.
NPJ Vaccines 4: 42.
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Millies B, von Hammerstein F, Gellert A, Hammerschmidt S, Barthels F, Göppel U, Immerheiser M, Elgner F, Jung N, Basic M, Kersten C, Kiefer W, Bodem J, Hildt E, Windbergs M, Hellmich UA, Schirmeister T (2019): Proline-Based Allosteric Inhibitors of Zika and Dengue Virus NS2B/NS3 Proteases.
J Med Chem 62: 11359-11382.
Online-Abstract

Milligan GN, Schnierle BS, McAuley AJ, Beasley DWC (2019): Defining a correlate of protection for chikungunya virus vaccines.
Vaccine 37: 7427-7436.
Online-Abstract

Müller C, Obermann W, Schulte FW, Lange-Grünweller K, Oestereich L, Elgner F, Glitscher M, Hildt E, Singh K, Hans-Guido W, Hartmann RK, Ziebuhr J, Grünweller A (2020): Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (-) and the eIF4A-inhibitor Silvestrol.
Antiviral Res 175: 104706.
Online-Abstract

Mulder AC, Kroneman A, Franz E, Vennema H, Tulen AD, Takkinen J, Hofhuis A, Adlhoch C, Members of HEVnet, Aberle S, Subissi L, Suin V, Midgley S, Kuznetsova T, Izopet J, Pavio N, Baechlein C, Baylis SA, Corman VM, Faber M, Johne R, Kamp C, Wenzel JJ, Coughlan S, Di Bartolo I, Bruni R, Ciccaglione AR, Garbuglia AR, Suffredini E, Boxman I, Hogema B, van der Poel W, Zaaijer H, de Sousa R, Velebit B, Avellón A, Buti M, Girones R, Quer J, Widén F, Norder H, Nyström K, Bachofen C, Sahli R, Dalton H, Ijaz S, Treagus S, Kulka M, Rizzi V (2019): HEVnet: a One Health, collaborative, interdisciplinary network and sequence data repository for enhanced hepatitis E virus molecular typing, characterisation and epidemiological investigations.
Euro Surveill 24: 1800407.
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Peiffer KH, Spengler C, Basic M, Jiang B, Kuhnhenn L, Obermann W, Zahn T, Glitscher M, Loglio A, Facchetti F, Carra G, Kubesch A, Vermehren J, Knop V, Graf C, Dietz J, Finkelmeier F, Hermann E, Trebicka J, Grünweller A, Zeuzem S, Sarrazin C, Lampertico P, Hildt E (2020): Quadruple mutation GCAC1809-1812TTCT acts as a biomarker in healthy European HBV carriers.
JCI Insight 5: e135833.
Online-Abstract

Rabenau HF, Schwebke I, Blümel J, Eggers M, Glebe D, Sauerbrei A, Steinmann E, Steinmann J, Willkommen H, Wutzler P (2020): Guideline for testing chemical disinfectants regarding their virucidal activity within the field of human medicine as of December 1st, 2014: Prepared by the German Association for the Control of Virus Diseases (DVV) and the Robert Koch Institute (RKI).
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 645-655.
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Rabenau HF, Schwebke I, Blümel J, Eggers M, Rapp I, Steinmann J, Willkommen H (2020): Comment on the Significance, Application and Determination of the Large Volume Plating (LVP) : 2. Communication of the DVV/GfV Virus Disinfection Expert Committee on the DVV/RKI Guideline in the Version of December 1st, 2014.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 657-659.
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Roth H, Schneider L, Eberle R, Lausen J, Modlich U, Blümel J, Baylis SA (2020): Zika Virus Infection Studies With CD34 + Hematopoietic and Megakaryocyte-Erythroid Progenitors, Red Blood Cells and Platelets.
Transfusion 60: 561-574.
Online-Abstract

Sabino C, Basic M, Bender D, Elgner F, Himmelsbach K, Hildt E (2019): Bafilomycin A1 and U18666A Efficiently Impair ZIKV Infection.
Viruses 11: 524.
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Scheiblauer H, Heiden M, Funk MB, Oberle D, Kreß J, Jork C, Chudy M (2020): Detection of hepatitis B virus infection in German blood donors 2008-2015.
Vox Sang 115: 152-161.
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Schnierle BS (2020): A New Host Factor Essential for Chikungunya Virus.
Trends Microbiol 28: 2-4.
Online-Abstract

Schnierle BS (2019): Cellular Attachment and Entry Factors for Chikungunya Virus.
Viruses 11: 1078.
Online-Abstract

Sliva K, Martin J, von Rhein C, Herrmann T, Weyrich A, Toda M, Schnierle BS (2019): Interference with SAMHD1 Restores Late Gene Expression of Modified Vaccinia Virus Ankara in Human Dendritic Cells and Abrogates Type I Interferon Expression.
J Virol 93: e01097-19.
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Tabari D, Scholl C, Steffens M, Weickhardt S, Elgner F, Bender D, Herrlein ML, Sabino C, Semkova V, Peitz M, Till A, Brüstle O, Hildt E, Stingl J (2020): Impact of Zika Virus Infection on Human Neural Stem Cell MicroRNA Signatures.
Viruses 12: 1219.
Online-Abstract

Tonnerre P, Melgaço JG, Torres-Cornejo A, Pinto MA, Yue C, Blümel J, de Sousa PSF, de Mello VDM, Moran J, de Filippis AMB, Wolski D, Grifoni A, Sette A, Barouch DH, Hoogeveen RC, Baylis SA, Lauer GM, Lewis-Ximenez LL (2020): Evolution of the innate and adaptive immune response in women with acute Zika virus infection.
Nat Microbiol 5: 76-83.
Online-Abstract

Vieths S, Hildt E, van Zandbergen G (2020): Immuntherapien - Wo stehen wir?.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1319-1321.
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von Rhein C, Scholz T, Henss L, Kronstein-Wiedemann R, Schwarz T, Rodionov RN, Corman VM, Tonn T, Schnierle BS (2021): Comparison of potency assays to assess SARS-CoV-2 neutralizing antibody capacity in COVID-19 convalescent plasma.
J Virol Methods 288: 114031.
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Wagner R, Hildt E (2019): Zusammensetzung und Wirkmechanismen von Adjuvanzien in zugelassenen viralen Impfstoffen.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 62: 462-471.
Online-Abstract

Wen X, Sun D, Guo J, Elgner F, Wang M, Hildt E, Cheng A (2019): Multifunctionality of structural proteins in the enterovirus life cycle.
Future Microbiol 14: 1147-1157.
Online-Abstract

Yang B, Wang H, Kaleas K, Butler M, Franklin J, Bill A, Baylis SA, Chen Q, Blümel J (2020): Clearance of Porcine Circovirus and Porcine Parvovirus From Porcine-Derived Pepsin by Low pH Inactivation and Cation Exchange Chromatography 7-2018.
Biotechnol Prog 36: e2968.
Online-Abstract

Yue C, Teitz S, Miyabashi T, Boller K, Lewis-Ximinez LL, Baylis SA, Blümel J (2019): Inactivation and Removal of Chikungunya Virus and Mayaro Virus from Plasma-derived Medicinal Products.
Viruses 11: 234.
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Zahn T, Akhras S, Spengler C, Murra RO, Holzhauser T, Hildt E (2020): A new approach for therapeutic vaccination against chronic HBV infections.
Vaccine 38: 3105-3120.
Online-Abstract

Zell R, Groth M, Krumbholz A, Lange J, Philipps A, Dürrwald R (2020): Displacement of the Gent/1999 human-like swine H1N2 influenza A virus lineage by novel H1N2 reassortants in Germany.
Arch Virol 165: 55-67.
Online-Abstract

Zell R, Groth M, Krumbholz A, Lange J, Philipps A, Dürrwald R (2020): Novel reassortant swine H3N2 influenza A viruses in Germany.
Sci Rep 10: 14296.
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Forschungsgruppe: Zelluläre Aspekte von Pathogen-Wirt-Interaktionen

Bergez M, Weber J, Riess M, Erdbeer A, Seifried J, Stanke N, Munz C, Hornung V, König R , Lindemann D (2019): Insights into Innate Sensing of Prototype Foamy Viruses in Myeloid Cells.
Viruses 11: 1095.
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Crauwels P, Bank E, Walber B, Wenzel UA, Agerberth B, Negatue MC, Alemayehu MA, König R, Ritter U, Reiling N, van Zandbergen G (2019): Cathelicidin mediated elimination of Leishmania in human host macrophages.
Front Immunol 10: 2697.
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Fuchs NV, Schieck M, Neuenkirch M, Tondera C, Schmitz H, des Portes V, Germanaud D, Steinemann D, Göhring G, König R (2019): Induced pluripotent stem cells (iPSCs) derived from a renpenning syndrome patient with c.459_462delAGAG mutation in PQBP1 (PEIi001-A).
Stem Cell Res 41: 101592.
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Fuchs NV, Schieck M, Neuenkirch M, Tondera C, Schmitz H, Steinemann D, Göhring G, König R (2020): Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual.
Stem Cell Res 42: 101679.
Online-Abstract

Fuchs NV, Schieck M, Neuenkirch M, Tondera C, Schmitz H, Wendeburg L, Steinemann D, Elpers C, Rutsch F, König R (2020): Generation of three induced pluripotent cell lines (iPSCs) from an Aicardi-Goutières syndrome (AGS) patient harboring a deletion in the genomic locus of the sterile alpha motif and HD domain containing protein 1 (SAMHD1).
Stem Cell Res 43: 101697.
Online-Abstract

Karamloo F, König R (2020): SARS-CoV-2 immunogenicity at the crossroads.
Allergy 75: 1822-1824.
Online-Abstract

Lauterbach-Rivière L, Bergez M, Mönch S, Qu B, Riess M, Vondran FWR, Liese J, Hornung V, Urban S, König R (2020): Hepatitis B Virus DNA Is a Substrate for the cGAS/STING Pathway but Is Not Sensed in Infected Hepatocytes.
Viruses 12: E592.
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Majer C, Schüssler JM, König R (2019): Intertwined: SAMHD1 cellular functions, restriction, and viral evasion strategies.
Med Microbiol Immunol 208: 513-529.
Online-Abstract

Osei Kuffour E, König R, Häussinger D, Schulz WA, Münk C (2019): ISG15 Deficiency Enhances HIV-1 Infection by Accumulating Misfolded p53.
MBio 10: e01342-19.
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Osundare FA, Klink P, Majer C, Akanbi OA, Wang B, Faber M, Harms D, Bock CT, Opaleye OO (2020): Hepatitis E Virus Seroprevalence and Associated Risk Factors in Apparently Healthy Individuals from Osun State, Nigeria.
Pathogens 9: 392.
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Patasic L, Seifried J, Bezler V, Kaljanac M, Schneider IC, Schmitz H, Tondera C, Hartmann J, Hombach A, Buchholz CJ, Abken H, König R, Cichutek K (2020): Designed Ankyrin Repeat Protein (DARPin) to target chimeric antigen receptor (CAR)-redirected T cells towards CD4 + T cells to reduce the latent HIV + cell reservoir.
Med Microbiol Immunol 209: 681-691.
Online-Abstract

Reimann M, Schrezenmeier JF, Richter-Pechanska P, Dolnik A, Hick TP, Schleich K, Cai X, Fan DNY, Lohneis P, Masswig S, Denker S, Busse A, Knittel G, Flümann R, Childs D, Childs L, Gätjens-Sanchez AM, Bullinger L, Rosenwald A, Reinhardt HC, Schmitt CA (2020): Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas.
Blood Nov 24 [Epub ahead of print].
Online-Abstract

Yin X, Langer S, Zhang Z, Herbert KM, Yoh S, König R, Chanda SK (2020): Sensor Sensibility-HIV-1 and the Innate Immune Response.
Cells 9: 254.
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Forschungsgruppe: Elektronenmikroskopie von Pathogenen

Blanco-Rodriguez G, Gazi A, Monel B, Frabetti S, Scoca V, Mueller F, Schwartz O, Krijnse Locker J, Charneau P, Di Nunzio F (2020): Remodeling of the Core Leads HIV-1 Preintegration Complex Into the Nucleus of Human Lymphocytes.
J Virol 94: e00135-20.
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Turonova B, Sikora M, Schürmann C, Hagen WJH, Welsch S, Blanc FEC, Bülow von S, Gecht M, Bagola K, Hörner C, van Zandbergen G, Mosalaganti S, Schwarz A, Covino R, Mühlebach MD, Hummer G, Krijnse Locker J, Beck M (2020): In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges.
Science 370: 203-208.
Text

Prüflabor für In-vitro-Diagnostika (IVD)

Fiedler SA, Oberle D, Chudy M, Scheiblauer H, Henseler O, Halbauer J, Heiden M, Funk MB (2019): Effectiveness of blood donor screening by HIV, HCV, HBV‐NAT assays, as well as HBsAg and anti‐HBc immunoassays in Germany (2008–2015).
Vox Sang 114: 443-450.
Online-Abstract

Henss L, Scholz T, von Rhein C, Wieters I, Borgans F, Eberhardt FJ, Zacharowski K, Ciesek S, Rohde G, Vehreschild M, Stephan C, Wolf T, Hofmann-Winkler H, Scheiblauer H, Schnierle BS (2020): Analysis of humoral immune responses in SARS-CoV-2 infected patients.
J Infect Dis 223: 56-61.
Online-Abstract

Mbunkah HA, Reinhardt J, Kafere C, Scheiblauer H, Prat I, Nübling CM (2021): In vitro diagnostics for screening the blood supply: the new European regulation for IVD and the WHO IVD prequalification programme.
Vox Sang 116: 3-12.
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Meyer T, Eberle J, Roß RS, Schüttler CG, Baier M, Buder S, Kohl PK, Münstermann D, Hagedorn HJ, Nick S, Jansen K, Bremer V, Mau M, Brockmeyer NH (2020): Schnelltestdiagnostik sexuell übertragbarer Infektionen: Gemeinsame Stellungnahme von DSTIG, RKI, PEI sowie den Referenzzentren für HIV, HBV und HCV und Konsiliarlaboren für Chlamydien, Gonokokken und Treponema pallidum.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63: 1271-1286.
Online-Abstract

Scheiblauer H, Heiden M, Funk MB, Oberle D, Kreß J, Jork C, Chudy M (2020): Detection of hepatitis B virus infection in German blood donors 2008-2015.
Vox Sang 115: 152-161.
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