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Data & Facts

Data & Facts

Externally funded Projects

Externally funded Projects

In 2019/2020, Paul-Ehrlich-Institut raised over 4 Million Euros more in third-party-funding than in 2017/2018

BMG | Federal Ministry of Health (2.619.235 €)

Project ManagerName of the ProjectDuration
Dr Christoph ConradGHPP Global Health Protection Programme RegTrain-VaccTrain:
Regulatory training and consulting for vaccines and biomedical therapeutics
01.01.19 - 31.12.20
Dr Anneliese HilgerGHPP Global Health Protection Programme BloodTrain: Availability, safety and quality of blood and blood products01.01.19 - 31.12.20
Prof. Dr Gerald G. SchumannSafety of human pluripotent stem cells used for somatic cell therapy01.01.19 - 31.12.21

BMBF | Federal Ministry of Education and Research (2.068.550 €)

Project ManagerName of the ProjectDuration
Dr Christoph ConradPDU CARB-X-Accelerator: Project management, consulting and regulatory aspects of antibiotic development01.01.19 - 31.12.21
Dr Christoph ConradDZIF-OSRA: German Center for Infection Research - Office for Scientific and Regulatory Advice01.01.19 - 28.02.21
Prof. Dr Eberhard Hildt Hepatitis B Cure: Development of a therapeutic vaccine against HBV based on HBV antigen-presenting cell-permeable VLPs01.01.19 - 28.02.21
PD Dr Michael MühlebachRecombinant measles virus as vaccine platform01.01.19 - 28.02.21
Prof. Dr Isabelle Bekeredjian-DingCOMBINE: Collaboration for prevention and treatment of MDR bacterial infections - Preparation of a IMI-EU application phase II01.02.19 - 31.12.19
Prof. Dr Stefan ViethsDIFAMEM: Dietary intervention in food allergy - microbiome, epigenetic and metabolomic interactions
01.03.19 - 28.02.22
Dr Heike Behrensdorf-Nicol
Dr Birgit Kegel
Alternative methods to animal testing: BoNT collaborative study on the implementation of the BINACLE assay for in vitro activity determination of botulinum neurotoxins01.04.19 - 31.03.21
Prof. Dr Isabelle Bekeredjian-DingAlternative methods to animal testing: B-CELL-ACT - Functional assay for B cell activation by toxoid vaccines01.04.19 - 31.03.22
Dr Verena Klümpers
PD Dr Micha Nübling
Dr Alexander Pinz
BISKIT: Blood Information System for Crisis Intervention and Management
Subprojekt: Processes und Structure
01.04.20 - 31.03.23
PD Dr Michael MühlebachMeV-derived vaccine candidates protecting against COVID-1915.04.20 - 14.04.21

DFG | German Research Foundation (2.115.295 €)

Project ManagerName of the ProjectDuration
Dr Stephan ScheurerImmune modulating mechanisms of flagellin A (FlaA)-fusion proteins at the interface between cell metabolism, TLR signaling, and inflammasome activation
WP2: TLR5/NLRC4-mediated activation
01.03.19 - 28.02.22
PD Dr Stefan Schülke

Immune modulating mechanisms of flagellin A (FlaA)-fusion proteins at the interface between cell metabolism, TLR signaling, and inflammasome activation

WP1: Immune metabolism

01.05.19 - 30.04.22
PD Dr Thorsten Jürgen MaierStudies on novel cysteine-reactive nitro fatty acids with covalent attack on inflammation-related drug targets01.11.19 - 31.10.22
Prof. Dr Zoltan IvicsModeling cerebellar pathology in ataxia-telangiectasia: study of ATM-deficient mice versus human iPS cells01.01.20 - 31.12.22
Prof. Dr Dr Ute ModlichHematopoietic stem cell-directed gene therapy for the treatment of ataxia telangiectasia (A-T)01.04.20 - 31.03.23
Prof. Dr Dr Ute ModlichEpcr expression and Epcr/Par1 signaling pathways in Mpl-deficient and normal hematopoiesis during transplantation01.06.20 - 31.05.23
Prof. Dr Ralf Reinhard TönjesBiology of xenogeneic cell, tissue and organ transplantation from basic research to clinical application. 01.07.20 - 30.06.24
Dr Renate König Investigation into the cellular mechanisms of the PQBP1-mediated innate immune response to HIV-101.10.20 - 30.09.23
Prof. Dr Ger van ZandbergenCell death dependence of leishmanial exit from infected host macrophages01.12.20 - 30.11.23

EU | European Union (3.638.280 €)

Project ManagerName of the ProjectDuration
Prof. Dr Christian BuchholzSTACCATO: Enhancing the manufacture of advanced biological medicine through high-resolution analysis of single cells01.01.19 - 31.12.22
Bettina ZiegeleSTARS: Strengthening Training of Academia in Regulatory Sciences and supporting regulatory scientific advice01.01.19 - 31.12.21
Prof. Dr Eberhard Hildt ERASMUS Grant Patrycja Dudek: Characterization of turnover of HCV non-structural proteins08.07.19 - 21.09.19
01.10.19 - 15.05.20
Prof Dr Ger van ZandbergenERASMUS Grant Fenja Gierschek: Characterization of immunomodulatory conditions in a human in vitro Leishmania infection model02.09.19 - 31.01.20
Prof. Dr Isabelle Bekeredjian-DingCollaboration for prevention and treatment of multidrug resistent (MDR) bacterial infections01.11.19 - 31.10.25
PD Dr Benjamin HofnerIntegrated research platforms enabling patient-centric drug development01.11.19 - 30.04.23
Prof. Dr Zoe WaiblerEmerging translational safety technologies and tools for interrogating human immuno-biology01.11.19 - 31.10.25
Prof. Dr Isabelle Bekeredjian-DingTIPAT: Training towards Personalized Antibiotic Treatment01.03.20 - 29.02.24

LOEWE Centers, Federal State of Hesse (486.850 €)

Project ManagerName of the ProjectDuration
Prof. Dr Christian BuchholzFrankfurt Cancer Institute: Assessing a CD3-targeted vector for in vivo CAR T cell generation01.01.19 - 31.12.19
Prof. Dr Zoltan IvicsFrankfurt Cancer Institut: CAR NK cell engineering using non-viral Sleeping Beauty transposition for novel design of therapy against malignant disease01.01.19 - 31.12.19
Prof. Dr Eberhard Hildt Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases (DRUID): Control of Arbovirus infection by interference with the early infection steps01.07.19 - 30.09.20
Prof. Dr. Barbara SchnierleDRUID: Implementation of a Chikungunya virus vaccine candidate based on self-amplifying RNA01.10.19 - 30.09.20
01.10.20 - 30.09.21
Dr Daniela BenderDRUID: Characterisaton of the ZIKV/host interaction01.12.19 - 31.05.20
Prof. Dr Jacomina Krijnse-LockerDRUID: Correlated light- and electron microscopy reveals virus entry and disassembly01.01.20 - 31.12.21
Prof. Dr Eberhard Hildt DRUID: New aspects of established drugs - cholesterol modulators efficiently block HEV replication01.07.20 - 31.12.21
Prof Dr Ger van ZandbergenDRUID: Parallel in vitro and in silico screening of small-molecule libraries against the key Leishmania enzyme glucose-6-phosphate dehydrogenase to identify first lead candidates01.07.20 - 31.12.21

Foundation and other Organisation (1.336.594 €)

ISBT | International Society of Blood Ttransfusion

Project ManagerName of the ProjectDuration
Dr Marcel PraxEstablishment of platelet bacterial reference strains in BioBall formatfrom 2019

Cystic Fibrosis Institute

Project ManagerName of the ProjectDuration
Dr Melanie AlbrechtT cell epithelial crosstalk via IL-17A and IL-22 in CF lung disease01.02.19 - 30.04.20

FEI | Research Association of the German Food Industry e.V.

Project ManagerName of the ProjectDuration
Prof. Dr Stefan Vieths
Dr Stephan Scheurer
Investigation of the health-promoting effect of pectins in food allergies01.04.19 - 30.09.2021

NIH | National Institute of Health

Project ManagerName of the ProjectDuration
Prof. Dr Christian BuchholzDisabling the replication-competent HIV provirus in the reservoir by combined CRISPR-Cas action05.04.2019 - 05.04.2023

Innovation Committee (Federal Joint Committee)

Project ManagerName of the ProjectDuration
Dr Brigitte Keller-StanislawskiVerSI-MS-PV – Making care safe - Feasibility study on the suitability of different data sources as a basis for improving the pharmacovigilance of innovative therapies using the example of multiple sclerosis01.06.2019 - 31.05.2022

Health Holland

Project ManagerName of the ProjectDuration
Prof. Dr Christian BuchholzLentiviral biological pacemakers01.03.2020 - 28.02.2022

BLE | Federal Office for Agriculture and Food

Project ManagerName of the ProjectDuration
Prof. Dr Stefan Vieths
Dr Melanie Albrecht
ZeBaP | Development and validation of a cell-based test system for detection of allergens and determination of allergenic potential of processed foods01.04.2020 - 31.03.2023

DAAD | German Academic Exchange Service / FEBS-Federation of European Biochemical Societies

Project ManagerName of the ProjectDuration
Dr Stephan Scheurer Grants Laura Martin Pedraza:
- Molecular characterization of Pru p 9, a novel PR-1 protein responsible for respiratory symptoms in peach tree pollen allergy
- Severe peach allergy with different sensitization routes:Pru p 9, a novel major allergen

01.10.20 - 31.12.20

01.01.21 - 31.03.21

DGUV | Statutory Accident Insurance

Project ManagerName of the ProjectDuration
Prof. Dr Vera Mahler  Quality assurance of the diagnosis of occupational type I allergies01.11.2020 - 31.10.2023

Polytechnical Society

Project ManagerName of the ProjectDuration
Prof. Dr Zoe WaiblerAnalysis of vWF-mediated effects on the immunogenicity of factor VIII products01.12.20-30.11.21

The totals represent the amount of external funding obtained.